53171-39-4

Basic information

• Product Name: METHYL SUCCINAMATE
• Synonyms: SUCCINAMIC ACID METHYL ESTER;METHYL SUCCINAMATE
• CAS NO: 53171-39-4
• Molecular Formula: C₅H₉NO₃
• Molecular Weight: 131.13
• Mol File: 53171-39-4.mol
• Article Data: 8

Chemical Properties

• Melting Point: 89 °C
• Boiling Point: 118 °C / 3mmHg
• Flash Point: 179.5 °C
• Appearance: /
• Density: 1.136 g/cm³
• Vapor Pressure: 0.00134mmHg at 25°C
• Refractive Index: 1.442
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 15.91±0.40(Predicted)
• CAS DataBase Reference: METHYL SUCCINAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL SUCCINAMATE(53171-39-4)
• EPA Substance Registry System: METHYL SUCCINAMATE(53171-39-4)

Safety Data

• Hazardous Substances Data: 53171-39-4(Hazardous Substances Data)

Usage

Uses

Methyl Succinamate is a useful synthetic intermediate. It is used to synthesize substituted oxazole-benzamide antibacterial inhibitors of FtsZ.

InChI:InChI=1/C5H9NO3/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H2,6,7)

Upstream product

• 4107-62-4 3-cyano-propionic acid methyl ester 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 638-32-4 succinamic acid 
• 106-65-0 Dimethyl succinate 
• 1490-25-1 succinic acid monomethylester chloride 
• 872805-52-2 3-carbamoyl-orthopropionic acid trimethyl ester 
• 123-56-8 Succinimide 

Downstream Products

• 123-56-8 Succinimide 
• 936850-80-5 3-[4-(4-trifluoromethyl-phenyl)-oxazol-2-yl]-propionic acid methyl ester 
• 1374746-30-1 C₁₁H₂₂N₂O₃ 
• 1249098-65-4 C₈H₁₆N₂O₃ 
• 100517-28-0 N,N'-carbonyl-di-β-alanine dimethyl ester 
• 1374746-29-8 C₁₀H₁₈N₂O₃ 
• 1252657-91-2 methyl 3-{4-[3,5-bis(trifluoromethyl)phenyl]-1,3-oxazol-2-yl}propanoate 

Relevant articles and documents

DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES

The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, which has a superior RBP4-lowering action and is useful as a pharmaceutical composition for the prophylaxis or treatment of a disease or condition mediated by an increase in RBP4.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.

Selective ammonolysis and aminolysis of dimethyl succinate. Synthesis of optically active N-alkylsuccinimides

Candida antarctica lipase catalyzes the selective monoammonolysis and aminolysis of dimethyl succinate with ammonia and aliphatic amines, respectively, in dioxane as solvent. This enzyme shows a high enantioselectivity when racemic amines are used. Optically active amidoesters are also obtained in the reaction of dimethyl succinate with racemic α-methylalkylamines in hexane as solvent. In this medium, the enzyme catalyzes the formation of N-alkylsuccinimides or optically active N-alkyl-α-methylsuccinimides from dimethyl succinate or α-methylsuccinate and amines.