53187-98-7 Usage
Description
11-ketotestosterone, also known as 11-oxotestosterone, is a synthetic steroid hormone derived from testosterone. It is structurally similar to testosterone but with an additional ketone group at the 11-beta position. This modification gives it unique properties and makes it a valuable compound for various applications in different fields.
Uses
Used in Analytical Chemistry:
11-ketotestosterone is used as a reference compound for the analysis of 52 C19 and C21 steroids by UPC2-MS/MS (Ultra-High-Performance Convergence Chromatography Tandem Mass Spectrometry). This technique allows for the separation, identification, and quantification of various steroid hormones and their metabolites in complex biological samples.
Used in Endocrinology Research:
11-ketotestosterone is used as a research tool for characterizing the C11-oxy steroid metabolome in serum. The study of steroid metabolites, particularly those with a hydroxyl group at the C11 position, can provide valuable insights into the regulation of steroid hormone synthesis, metabolism, and their role in various physiological processes.
Used in Pharmaceutical Industry:
11-ketotestosterone can be used as an active pharmaceutical ingredient in the development of drugs targeting steroid hormone-related conditions. Its unique structural features and biological activities make it a promising candidate for the treatment of various disorders related to steroid hormone imbalances.
Used in Sports Medicine:
11-ketotestosterone may be used as a performance-enhancing substance in sports, although its use is generally prohibited due to its anabolic and androgenic effects. It can potentially improve athletic performance by increasing muscle mass, strength, and endurance.
Used in Veterinary Medicine:
In veterinary medicine, 11-ketotestosterone can be used for the treatment of certain hormonal imbalances in animals, such as reproductive disorders or growth issues. Its application in this field can help improve the health and well-being of animals under veterinary care.
Check Digit Verification of cas no
The CAS Registry Mumber 53187-98-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,1,8 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 53187-98:
(7*5)+(6*3)+(5*1)+(4*8)+(3*7)+(2*9)+(1*8)=137
137 % 10 = 7
So 53187-98-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,16-17,22H,3-8,10H2,1-2H3/t13-,14-,16?,17+,18-,19-/m0/s1
53187-98-7Relevant articles and documents
INTRAMOLECULAR DIELS-ALDER REACTION WITH FURAN-DIENE. TOTAL SYNTHESIS OF (+/-)-11-KETOTESTOSTERONE AND (+/-)-ADRENOSTERONE.
Royen, Luc A. Van,Mijngheer, Roelant,Clercq, Pierre J. De
, p. 4667 - 4680 (2007/10/02)
A novel D BCD ABCD route to 11-keto steroids is reported involving a high yield stereoselective intramolecular Diels-Alder reaction of furan-diene 12 in water as a key-step.The dienophilic side chain is readily introduced starting from 8 via a sequence involving alkylation with ethyl (E)-3-ethoxy-4-iodo-2-butenoate, reduction and acid hydrolysis.The reduced adduct 14 is further converted into (+/-)-adrenosterone (6) via 24, the dienediolate equivalent of which is a known intermediate in corticosteroid synthesis.
