536-89-0

Basic information

• Product Name: M-TOLYLHYDRAZINE
• Synonyms: (3-methyl-phenyl)-hydrazine;M-TOLYLHYDRAZINE;(m-Methylphenyl)hydrazine;1-(3-Methylphenyl)hydrazine;M-Tolylhydrazine. HCL froM;m-tolylhydrazine HCl
• CAS NO: 536-89-0
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• EINECS: 208-650-9
• Mol File: 536-89-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 192-193 °C (decomp)
• Boiling Point: 132-134°C 16mm
• Flash Point: 132-134°C/16mm
• Appearance: /
• Density: 1,057 g/cm3
• Refractive Index: 1.5890
• PKA: 5.35±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• Merck: 14,9542
• BRN: 742264
• CAS DataBase Reference: M-TOLYLHYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: M-TOLYLHYDRAZINE(536-89-0)
• EPA Substance Registry System: M-TOLYLHYDRAZINE(536-89-0)

Safety Data

• Statements: 20/21/22
• Safety Statements: 36/37
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 536-89-0(Hazardous Substances Data)

Usage

Uses

m-Tolylhydrazine is used as pharmaceutical intermediate. It reacts with cyclohexanone and obtain the 7-methyl-1,2,3,4-tetrahydro-carbazole.

InChI:InChI=1/C7H10N2/c1-6-3-2-4-7(5-6)9-8/h2-5,9H,8H2,1H3

Upstream product

• 2028-72-0 m-toluenediazonium chloride 
• 108-44-1 1-amino-3-methylbenzene 
• 625-95-6 3-Iodotoluene 
• 591-17-3 meta-bromotoluene 
• 108-41-8 1-chloro-3-methylbenzene 
• 7647-01-0 hydrogenchloride 
• 63815-25-8 3-methylbenzene diazonium 

Downstream Products

• 35496-20-9 5-methyl-2-m-tolyl-1,2-dihydro-pyrazol-3-one 
• 62698-28-6 benzaldehyde m-tolylhydrazone 
• 52722-67-5 α-(N'-m-tolyl-hydrazino)-isobutyronitrile 
• 54381-25-8 2-methylpropanoic acid 2-(3-methylphenyl)hydrazide 
• 538-00-1 1-m-tolyl semicarbazide 
• 1025452-19-0 C₂₀H₂₀N₄S 
• 1152594-11-0 1-(3'-methylphenyl)-3-phenyl-2-pyrazolin-5-one 
• 1200832-77-4 N-(3-Chloro-1-benzothien-2-yl)-2-(3-methylphenyl)-hydrazinocarboxamide 
• 41931-13-9 LCS-1 
• 92721-83-0 3‐methyl‐1‐(3‐methylphenyl)‐1H‐pyrazol‐5‐amine 
• 1028279-76-6 4-ethoxycarbonyl-1-(3-methylphenyl)-3-pyrazolin-5-one 

Relevant articles and documents

Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine

In this work, we developed a ligand- and base-free visible-light-mediated protocol for the photoredox syntheses of arylphosphonates and, for the first time, alkyl phosphonates. Zinc phthalocyanine-photocatalyzed Csp2-P and Csp3-P bond formations were efficiently achieved by reacting aryl/alkylhydrazines with trialkylphosphites in the presence of air serving as an abundant oxidant. The reaction conditions tolerated a wide variety of functional groups.

Preparation method of 3-methyl phenylhydrazine oxalate

The invention relates to a preparation method of 3-methyl phenylhydrazine oxalate. The preparation method comprises the following steps: diazotization, reduction, purification and salt formation. In the diazotization and reduction steps, reaction liquid is kept with high acidity by means of concentrated hydrochloric acid, so that the reaction is smoothly and fully carried out. In the reduction step, zinc powder-concentrated hydrochloric acid is taken as a reducing agent to replace sodium thiosulfate, sodium hydrogen sulfite, stannous chloride-hydrochloric and the like, the reducing property isgood, the yield is high, the reaction time is shortened, impurities such as zinc hydroxide generated by the reaction are conveniently removed, and the product is few in impurity and high in purity. In the salt formation step, acetone is used to wash, so that the purity of the product is improved, and the appearance of the product is ensured. According to the preparation method, the process is stable and reliable, the operation is easy, the product purity is high (the content of the product detected by high performance liquid chromatography is greater than or equal to 99%), the yield is greater than or equal to 42%, and the demand on 3-methyl phenylhydrazine oxalate in the market is fully met.

Remazol-Catalyzed Hydroperoxyarylation of Styrenes

A mild photocatalytic hydroperoxyarylation of styrenes has been developed, in which a novel photocatalyst, remazol brilliant blue R (RBBR), is employed at low catalytic loading (1 mol%). The operationally easy procedure uses air as the dioxygen source. Simple mono-substituted styrenes react with aryl hydrazines in moderate-to-good yields. RBBR is proposed to act as a photosensitizer for the generation of singlet oxygen.