53636-17-2

Basic information

• Product Name: (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL
• Synonyms: (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL;(S)(+)-L-DIMETHYLAMINO-2-PROPANOL;(2S)-1-(Dimethylamino)-2-propanol;(S)-1-(dimethylamino)propan-2-ol;(S)-Dimepranol;L-(+)-1-(Dimethylamino)propan-2-ol;(2S)-1-(Dimethylamino)propan-2-ol
• CAS NO: 53636-17-2
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16
• Product Categories: Amino Alcohols;Chiral Building Blocks;Organic Building Blocks
• Mol File: 53636-17-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 29.84°C (estimate)
• Boiling Point: 121-127 °C(lit.)
• Flash Point: 22 °C
• Appearance: /
• Density: 0.837 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.419(lit.)
• PKA: 14.95±0.20(Predicted)
• CAS DataBase Reference: (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL(53636-17-2)
• EPA Substance Registry System: (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL(53636-17-2)

Safety Data

• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 16-26-27-36/37/39-45
• RIDADR: UN 2733 3/PG 2
• Hazardous Substances Data: 53636-17-2(Hazardous Substances Data)

Usage

General Description

(S)-(+)-1-DIMETHYLAMINO-2-PROPANOL is a chemical compound that belongs to the class of alcohols. It is a colorless liquid with a fishy odor and is soluble in water. (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL is commonly used as a solvent and as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also used in the production of quaternary ammonium compounds, which are commonly used as surfactants and disinfectants. Additionally, (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL is utilized in the manufacturing of agricultural chemicals and as a corrosion inhibitor in metalworking fluids. It is important to handle this compound with care, as it can cause irritation to the skin and eyes upon contact.

InChI:InChI=1S/C5H13NO/c1-5(7)4-6(2)3/h5,7H,4H2,1-3H3/t5-/m0/s1

Upstream product

• 108-16-7 1-methyl-2-N,N-dimethylaminoethanol 
• 15364-56-4 dimethylaminoacetone 
• 108-05-4 vinyl acetate 
• 105-38-4 vinyl propionate 
• 98956-88-8 1-(dimethylamino)-2-propanyl butyrate 
• 50-00-0 formaldehyd 
• 2799-17-9 (S)-1-amino-2-propanol 
• 687-47-8 (S)-Ethyl lactate 
• 124-40-3 dimethyl amine 
• 31502-31-5 (S)-N,N-dimethyl lactamide 
• 32464-98-5 (2S)-2-hydroxypropyl 4-methylbenzenesulfonate 

Downstream Products

• 6134-96-9 (S)-4-dimethylamino-3-methyl-2.2-diphenyl-butyronitrile 

Relevant articles and documents

Simple one-pot process for the bioresolution of tertiary amino ester protic ionic liquids using subtilisin

An efficient hydrolase-catalyzed bioresolution of tertiary amino ester protic ionic liquids has been demonstrated. Protic ionic liquids have been prepared in one step from the corresponding tertiary amino alcohols by treatment with butyric anhydride. Afte

Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups

A process for preparing optically active secondary alcohols of the general formula (3), [wherein R1 is linear lower alkyl, an aromatic ring group, or the like; A is CH2NR2R3 or the like; n is an integer of 0 to 2; and * represents an asymmetric carbon atom] by asymmetrically hydrogenating a ketone compound of the general formula (1) having nitrogenous or oxygen functional group at any of the a-, β- and γ-positions, with selectivity among functional groups by the use of a ruthenium/optically active bidentate phosphine/diamine complex as the catalyst in the presence of hydrogen alone or together with a base. The optically active secondary alcohols obtained by the process are useful as drugs and intermediates for the preparation of drugs.

Asymmetric hydrogenation of amino ketones using chiral RuCl2(diphophine)(1,2-diamine) complexes [12]

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