53684-35-8

Basic information

• Product Name: trans-cinnamoylsulfamoyl chloride
• Synonyms: trans-cinnamoylsulfamoyl chloride
• CAS NO: 53684-35-8
• Molecular Weight: 245.686
• Mol File: 53684-35-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-cinnamoylsulfamoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: trans-cinnamoylsulfamoyl chloride(53684-35-8)
• EPA Substance Registry System: trans-cinnamoylsulfamoyl chloride(53684-35-8)

Safety Data

• Hazardous Substances Data: 53684-35-8(Hazardous Substances Data)

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 621-82-9 Cinnamic acid 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 1885-38-7 cinnamic nitrile 

Relevant articles and documents

The Introduction of Nitrile-Groups into Heterocycles and Concversion of Carboxylic Groups into their Corresponding Nitriles with Clorosulfonylisocyanate and Triethylamine

Addition of chlorosulfonylisocyanate (CSI) to heterocycles such as thiophene (4) or indole (15) and unsaturated systems such as dihydropyran (7) gives N-chlorosulfonylamides RCONHSO2Cl, which can be converted by equivalent amounts of triethylamine to their corresponding nitriles.Since carboxylic acids react with CSI to N-chlorosulfonylamides, subsequent treatment with triethylamine affords the corresponding nitriles, but no isocyanates as claimed by other authors.The mechanisms of the conversion of the intermediate N-chlorosulfonylamides into the corresponding nitriles are discussed.