53723-51-6Relevant articles and documents
Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans
Hanessian, Stephen,Szychowski, Janek,Pablo Maianti
supporting information; experimental part, p. 429 - 432 (2009/09/25)
(Chemical Equation Presented) A synthesis of verdamicin C2 and its congener C2a has been accomplished from sisomicin relying on a novel oxidative transformation of an allylic azide to the corresponding α,β- unsaturated aldehyde, and its stereocontrolled elaboration into the intended 5′ side chain of verdamicin C2 and C2a. In vitro antibacterial testing shows that both C6′ epimers in verdamicin C2 and C2a are equally active against a variety of bacterial strains. Oxidation of allylic primary azides, ethers, and esters of 2-substituted dihydro[2H]pyrans with SeO2 leads directly to the corresponding aldehydes.
THE NITROGENATED ALLYLIC SYSTEM AS AN INTRAMOLECULAR NUCLEOPHILE: A NEW ROUTE TO PYRAZOLES
Momose, Takefumi,Toyooka, Naoki,Ikuta, Takashi,Yanagino, Hironobu
, p. 789 - 793 (2007/10/02)
A new route to pyrazoles via the cyclization of N-allyl-N-nitrosoamides is described.
Obtention de composes ethyleniques difonctionnels par acetylation de cyclohexenes diversement substitues. Synthese d'esters d'acetyl cyclohexenyle
Grignon-Dubois, M.,Cazaux, M.
, p. 332 - 342 (2007/10/02)
A series of 22 functionally substituted (i. e. ketone, nitrile, ester and alcohol) cycloalkenes was treated with a complex of acetic anhydride-zinc chloride.The influence exerted on the reaction by the function's nature and its position relative to the do