53732-61-9

Basic information

• Product Name: 2-(phenylsulfanyl)benzoyl chloride
• CAS NO: 53732-61-9
• Molecular Formula: C₁₃H₉ClOS
• Molecular Weight: 248.728
• Mol File: 53732-61-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 346.3°C at 760 mmHg
• Flash Point: 163.3°C
• Density: 1.31g/cm³
• Vapor Pressure: 5.79E-05mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 2-(phenylsulfanyl)benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylsulfanyl)benzoyl chloride(53732-61-9)
• EPA Substance Registry System: 2-(phenylsulfanyl)benzoyl chloride(53732-61-9)

Safety Data

• Hazardous Substances Data: 53732-61-9(Hazardous Substances Data)

Usage

General Description

2-(phenylsulfanyl)benzoyl chloride, also known as thioandeloyl chloride, is a chemical compound with the molecular formula C14H9ClOS. It is a benzoyl chloride derivative with a sulfanyl group attached to the phenyl ring, making it a thioester. 2-(phenylsulfanyl)benzoyl chloride is widely used in organic synthesis as a key intermediate for the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. Additionally, it can be used as a reagent in the production of polymers and resins. Thioandeloyl chloride is known for its strong electrophilic nature due to the presence of the acyl chloride group, making it a useful reagent for reactions such as acylation and amidation. However, it is important to handle this compound with care due to its potential hazards, including its reactivity and corrosive properties.

Upstream product

• 1527-12-4 2-(phenylthio)benzoic acid 
• 108-86-1 bromobenzene 
• 147-93-3 Thiosalicylic acid 

Downstream Products

• 492-22-8 thio-xanthene-9-one 
• 176509-21-0 (2-Phenylsulfanyl-benzoyl)-phosphonic acid dimethyl ester 

Relevant articles and documents

COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME

An onium salt and a composition having high sensitivity and excellent pattern characteristics such as LWR, which is preferably used for a resist composition for a lithography process using two active energy rays of a first active energy ray such as an electron beam or an extreme ultraviolet and a second active energy ray such as UV.

Reactions of carbene intermediates from the reaction of trialkyl phosphites with dialkyl benzoylphosphonates: Intramolecular cyclisations of 2-substituted dialkyl benzoylphosphonates

The reaction of dialkyl benzoylphosphonates 1 with trialkyl phosphites leads to the formation of carbene intermediates 3 via the anionic intermediates 2. The carbene intermediates 3 (R = 2-PhO, 2-PhOCH2, and 2-PhS) have been generated by heating the corresponding 2-substituted dialkyl benzoylphosphonates with trimethyl phosphite and their subsequent reactions investigated. Reactions proceed either by intermolecular trapping of the carbene intermediates by trimethyl phosphite to give novel ylidic phosphonates 4, or by intramolecular routes involving carbene insertion into the π-system of the phenyl ring in the substituent. Studies using methyl-substituted derivatives have shown that the formation of the thioxanthenylphosphonate 15 (X = S, R′ = R″ = Me) proceeds via a spiro diene intermediate 14 (X = S, R′ = R″ = Me).