53844-46-5 Usage
Description
(+/-)-Isomyosmine is an organic compound that serves as a key intermediate in the synthesis of various chemical compounds, particularly in the production of (+/-)-N'-Nitrosonornicotine 5'-Acetate (NNN-5’-OAc), a stable precursor of the active metabolite 5'-hydroxy(+/-)-N'-nitrosonornicotine (NNN-5'-OH).
Uses
Used in Pharmaceutical Synthesis:
(+/-)-Isomyosmine is used as a synthetic intermediate for the production of (+/-)-N''-Nitrosonornicotine 5''-Acetate (NNN-5’-OAc), which is a stable precursor of the active metabolite 5''-hydroxy(+/-)-N''-nitrosonornicotine (NNN-5''-OH). This makes it an essential component in the development of pharmaceuticals targeting specific health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 53844-46-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,8,4 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53844-46:
(7*5)+(6*3)+(5*8)+(4*4)+(3*4)+(2*4)+(1*6)=135
135 % 10 = 5
So 53844-46-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5-7,9H,2,4H2
53844-46-5Relevant articles and documents
Enantioselective Synthesis of Nicotine via an Iodine-Mediated Hofmann-L?ffler Reaction
Del Castillo, Estefanía,Mu?iz, Kilian
supporting information, p. 705 - 708 (2019/02/07)
An iodine-mediated Hofmann-L?ffler reaction has been developed that enables the first enantioselective synthesis of nicotine based on this synthetic methodology. The effect of the free pyridine core on the involved electrophilic iodine reagents was explored in detail. The final synthesis proceeds under moderate reaction conditions that tolerate the free pyridine core. The same synthetic sequence is also applicable to a number of derivatives with higher substituted pyridine cores, including bipyridine derivatives.
Simple and versatile synthesis of 1-pyrroline derivatives through thermal rearrangement of N-cyclopropylimines
Campos, Pedro J.,Soldevilla, Alberto,Sampedro, Diego,Rodríguez, Miguel A.
, p. 8811 - 8813 (2007/10/03)
N-Cyclopropylimines rearrange under thermal conditions to give 1-pyrrolines. The effect of imine and cyclopropane substitution is explored. This methodology allows the presence of different substituents (alkyl, alkenyl, aryl) and the reaction proceeds reg
