539-21-9Relevant articles and documents
Kinetics of the transformation of dihydroambazone into ambazone in different solutions
Miosga,Roemer,Amlacher
, p. 41 - 42 (2007/10/02)
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539-21-9
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Basic information
- Product Name: Ambazone
- Synonyms: ambazone;p-benzoquinone amidinohydrazone thiosemicarbazone;1,4-Benzoquinone guanylhydrazone thiosemicarbazone;Faringosept;Inversal;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)-guanidin thiosemicarbazone;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)guanidine thiosemicarbazone;1-amidinohydrazono-4-thiosemicarbazono-2,5-cyclohexadiene
- CAS NO:539-21-9
- Molecular Formula: C8H11N7S
- Molecular Weight: 237.28484
- EINECS: 208-713-0
- Product Categories: Amines;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
- Mol File: 539-21-9.mol
- Article Data: 2
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Chemical Properties
- Melting Point: 195°C (rough estimate)
- Boiling Point: 160°C (rough estimate)
- Flash Point: 233.2°C
- Appearance: /
- Density: 1.2732 (rough estimate)
- Vapor Pressure: 1.03E-08mmHg at 25°C
- Refractive Index: 1.5500 (estimate)
- Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
- Solubility: DMSO (Slightly), Methanol (Slightly)
- Stability: Very Hygroscopic
- CAS DataBase Reference: Ambazone(CAS DataBase Reference)
- NIST Chemistry Reference: Ambazone(539-21-9)
- EPA Substance Registry System: Ambazone(539-21-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 539-21-9(Hazardous Substances Data)
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539-21-9 Usage
Originator
Ambazone,GenericUses
Ambazone is a benzoquidine diimine derivative useful as animal growth substance.Manufacturing Process
To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).Therapeutic Function
AntisepticCheck Digit Verification of cas no
The CAS Registry Mumber 539-21-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.Calculate Digit Verification of CAS Registry Number 539-21:
(5*5)+(4*3)+(3*9)+(2*2)+(1*1)=69
69 % 10 = 9
So 539-21-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4,12H,(H2,11,16)(H4,9,10,14)/b15-13+
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Ambazone
