5409-15-4

Basic information

• Product Name: 4-CHLORO-1-HYDROXY-2-NAPHTHOIC ACID
• Synonyms: 4-CHLORO-1-HYDROXY-2-NAPHTHOIC ACID;2-naphthalenecarboxylic acid, 4-chloro-1-hydroxy-;4-Chloro-1-hydroxynaphthalene-2-carboxylic acid;2-Naphthoic acid, 4-chloro-1-hydroxy-;4-chloro-1-hydroxy-2-naphthalenecarboxylic acid
• CAS NO: 5409-15-4
• Molecular Formula: C₁₁H₇ClO₃
• Molecular Weight: 222.62448
• EINECS: 226-477-7
• Mol File: 5409-15-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 393.1°C at 760 mmHg
• Flash Point: 191.5°C
• Appearance: /
• Density: 1.52g/cm³
• Vapor Pressure: 6.96E-07mmHg at 25°C
• Refractive Index: 1.719
• CAS DataBase Reference: 4-CHLORO-1-HYDROXY-2-NAPHTHOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-1-HYDROXY-2-NAPHTHOIC ACID(5409-15-4)
• EPA Substance Registry System: 4-CHLORO-1-HYDROXY-2-NAPHTHOIC ACID(5409-15-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5409-15-4(Hazardous Substances Data)

Usage

General Description

4-Chloro-1-hydroxy-2-naphthoic acid, also referred to as 4-chlorosalicylic acid, is an organochlorine compound often utilized in the chemical industry due to its properties. It is composed of chloro, hydroxy, and carboxy functional groups, which are attached to a naphthalene structure. Its molecular formula is C10H7ClO3, indicating ten carbon atoms, seven hydrogen atoms, one chlorine atom, and three oxygen atoms. The compound is known for its reactivity and is commonly used in reactions to form other complex organic molecules. Its potential applications and hazardous traits align with those typical of chlorinated aromatic compounds. Detailed information regarding its physical and chemical properties, including its melting point, boiling point, and density, may vary based on the specifics of its condition or form. It is crucial to handle and dispose of it properly to minimize potential threats to human health and the environment.

InChI:InChI=1/C11H7ClO3/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,13H,(H,14,15)

Upstream product

• 7791-25-5 sulfuryl dichloride 
• 873975-22-5 1,1'-dihydroxy-4,4'-sulfanediyl-di-[2]naphthoic acid 
• 71-43-2 benzene 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 
• 86-48-6 1-hydroxy-2-naphthoic acid 

Downstream Products

• 58132-06-2 chloro-4 formyl-2 hydroxy-1 naphtalene 
• 604-44-4 4-chloronaphthalen-1-ol 
• 408498-69-1 N-(4-chloro-1-hydroxy-2-naphthoylamido)-(L)-phenylalanine 
• 135241-08-6 3-chloro-4-hydroxynaphthalene-2-carboxylic acid methyl ester 
• 36268-75-4 4-chloro-1-hydroxy-[2]naphthoic acid phenyl ester 

Relevant articles and documents

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INHIBITORS OF CXCR2

The invention relates to compounds of the formula (I), in which R1, R2, X, A, B and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula (I) and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.