54130-93-7

Basic information

• Product Name: δ-(2,3-dimethoxyphenyl)valeric acid
• Synonyms: δ-(2,3-dimethoxyphenyl)valeric acid
• CAS NO: 54130-93-7
• Molecular Weight: 238.284
• Mol File: 54130-93-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: δ-(2,3-dimethoxyphenyl)valeric acid(CAS DataBase Reference)
• NIST Chemistry Reference: δ-(2,3-dimethoxyphenyl)valeric acid(54130-93-7)
• EPA Substance Registry System: δ-(2,3-dimethoxyphenyl)valeric acid(54130-93-7)

Safety Data

• Hazardous Substances Data: 54130-93-7(Hazardous Substances Data)

Upstream product

• 1378238-71-1 (Z)/(E)-5-(2',3'-dimethoxyphenyl)pent-4-enoic acid 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 67090-89-5 5-(2,3-Dimethoxyphenyl)penta-2,4-dienoic acid 

Downstream Products

• 1378238-73-3 1-((tert-butyldimethylsilyl)oxy)-2-methoxy-5-(3',4',5'-trimethoxyphenyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol 
• 1378238-98-2 1,2-dimethoxy-5-(3',4',5'-trimethoxyphenyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol 
• 1378238-99-3 3,4-dimethoxy-9-(3',4',5'-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene 
• 1378239-01-0 1,2-bis((tert-butyldimethylsilyl)oxy)-5-(3',4',5'-trimethoxyphenyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol 
• 1378239-02-1 (9-(3',4',5'-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene-3,4-diyl)bis(oxy)bis(tert-butyldimethylsilane) 
• 1378239-11-2 9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol 
• 1378239-13-4 3-methoxy-4-hydroxy-9-(3',4'-dihydroxy-5'-methoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene 
• 1378239-12-3 3,4-dimethoxy-9-(3',5'-dimethoxy-4'-hydroxyphenyl)-6,7-dihydro-5H-benzo[7]annulene 
• 1393587-93-3 2-methoxy-5-(3',4',5'-trimethoxyphenyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-1-ol 

Relevant articles and documents

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

The discovery of 3-methoxy-9-(3′,4′,5′-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulen-4-ol (a benzosuberene-based analogue referred to as KGP18) was originally inspired by the natural products colchicine and combretastatin A-4 (CA4). The relative struct

Efficient Method for Preparing Functionalized Benzosuberenes

The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reaction of a 5-phenylpentanoic acid with Eaton's reagent to form the benzosuberone. The process, optionally, further includes steps for adding a functional group at the ketone position.

Catecholamines in Rigid Framework: Synthesis and Pharmacological Evaluation of cis- and trans-6-Amino-1,2-dihydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ols

6-Amino-1,2-dihydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ols (cis-1 and trans-2), incorporating the α-rotameric form of norepinephrine in the trans-extended conformation have been synthesized and evaluated for their biological activity. trans-6-Amino-1,2-dihydroxy-6,7,8,9-tetrahydro-5H-benzocylohepten-5-ol (2) is found to possess marked β2-stimulant activity.