541540-90-3

Basic information

• Product Name: 2,5-BISCHLOROMETHYL-1,3,4-OXADIAZOLE
• Synonyms: 2,5-BISCHLOROMETHYL-1,3,4-OXADIAZOLE
• CAS NO: 541540-90-3
• Molecular Formula: C4H4Cl2N2O
• Molecular Weight: 166.99
• Product Categories: pharmacetical
• Mol File: 541540-90-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 252.3°C at 760 mmHg
• Flash Point: 106.4°C
• Appearance: /
• Density: 1.463g/cm³
• Vapor Pressure: 0.031mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 2,5-BISCHLOROMETHYL-1,3,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-BISCHLOROMETHYL-1,3,4-OXADIAZOLE(541540-90-3)
• EPA Substance Registry System: 2,5-BISCHLOROMETHYL-1,3,4-OXADIAZOLE(541540-90-3)

Safety Data

• Hazardous Substances Data: 541540-90-3(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Uses

Building block in the production of pharmaceuticals, agrochemicals, and other specialty chemicals; utilized in the manufacturing of polymers and plasticizers

Reactivity

High reactivity

Bonding

Ability to form strong covalent bonds

Antimicrobial properties

Potential antimicrobial and antifungal properties

Applications

Useful in various chemical reactions; valuable compound in the field of medicine and biotechnology.

InChI:InChI=1/C4H4Cl2N2O/c5-1-3-7-8-4(2-6)9-3/h1-2H2

Upstream product

• 89124-06-1 1,2-bis(chloroacetyl)hydrazide 
• 79-04-9 chloroacetyl chloride 

Relevant articles and documents

Design of a semirigid molecule as a selective fluorescent chemosensor for recognition of Cd(II)

(Chemical Equation Presented) (Graph Presented) A new 8-hydroxyquinoline- based chemosensor possessing a semirigid structure was designed, and its fluorescent sensing behavior toward metalions was investigated. A prominent fluorescence enhancement only for Cd2+ was found in aqueous methanol solution. The results clearly suggest that the specific semirigid structure could selectively accommodate Cd2+ according to ionic radius, which would effectively suppress the intramolecular radiationless transitions from the nπ* state to enhance the fluorescence response.

A highly sensitive and selective fluorescent probe for Fe3+ based on 2-(2-hydroxyphenyl)benzothiazole

A novel fluorescent Fe3+ probe (L)based on 2-(2-hydroxyphenyl) benzothiazole has been synthesized and characterized. Both UV-vis and fluorescence spectroscopic studies demonstrated that L was highly sensitive and selective towards Fe3+ over other metal ions in acetonitrile. Upon binding with Fe3+, the emission band of L red-shifted from 370 nm to 420 nm and the fluorescence intensity was enhanced ～103-fold. The lowest detection limit for L is 6.04 × 10-8 M and the dissociation constants Kd is 1.13 × 10-11 M, which were calculated from the fluorescence titration curves. The detailed UV-vis and fluorescent titrations studies suggested that the binding stoichiometry of the L-Fe3+ complex was 2:1, and the structure between L and the Fe 3+ complex was confirmed by the 1H NMR titration. Then IR spectra provided further proof of the binding mode of the L-Fe3+ complex.