5418-10-0 Usage
General Description
4-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine, also known as PD173955, is a small molecule compound that belongs to the family of pyrazolopyrimidine derivatives. It has been studied for its potential pharmacological properties, particularly its inhibitory effects on certain kinases. 4-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine has shown promising results in preclinical studies as an anti-cancer agent, with its ability to inhibit the growth of tumor cells. It has also been investigated for its potential in treating other diseases such as cardiovascular and inflammatory conditions. Its structure and properties make it a valuable tool for studying signal transduction pathways and developing targeted therapies. Further research and development are necessary to fully understand and harness the potential of 4-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine for therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5418-10-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,1 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5418-10:
(6*5)+(5*4)+(4*1)+(3*8)+(2*1)+(1*0)=80
80 % 10 = 0
So 5418-10-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N4S/c1-11-6-4-2-9-10-5(4)7-3-8-6/h2-3H,1H3,(H,7,8,9,10)
5418-10-0Relevant articles and documents
FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 45, (2011/06/19)
The present invention relates to Fused Bicyclic Pyrimidine Derivatives, compositions comprising a Fused Bicyclic Pyrimidine Derivative, and methods of using the Fused Bicyclic Pyrimidine Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G-protein coupled receptor (GPCR) in a patient.
Tricyclic base analogues
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, (2008/06/13)
Nucleoside analogues have structure (2) wherein Q is H or a sugar moiety or sugar analogue or a modified sugar or a nucleic backbone or backbone analogue, W is an alkylene or alkenylene chain of 0-5 carbon atoms, any of which may carry a substituent R8, X is O or N or NR12or CR10, X′ is O or S or N, provided that when X′ is O or S, then X is C, Y is CH or N, R6is NH2or SMe or SO2Me or NHNH2, each of R7and R8is independently H or F or alkyl or alkenyl or aryl or acyl or a reporter moiety, R12is independently H or alkyl or alkenyl or aryl or acyl or a reporter moiety, and R10is H or ═O or F or alkyl or aryl or a reporter moiety.
Purine analogues as amplifiers of phleomycin. V. Thioethers of several heterocyclic systems with one or two rings
Brown,Grigg,Iwai,et al.
, p. 2713 - 2726 (2007/10/04)
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