54276-22-1

Basic information

• Product Name: (+)-15(S)-CLOPROSTENOL
• Synonyms: D-Cloprostenol;15S-Cloprosteno
• CAS NO: 54276-22-1
• Molecular Formula: C₂₂H₂₉ClO₆
• Molecular Weight: 424.91506
• Mol File: 54276-22-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 628.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.321±0.06 g/cm3 (20 oC 760 Torr), Calc.*
• PKA: 4.76±0.10(Predicted)
• CAS DataBase Reference: (+)-15(S)-CLOPROSTENOL(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-15(S)-CLOPROSTENOL(54276-22-1)
• EPA Substance Registry System: (+)-15(S)-CLOPROSTENOL(54276-22-1)

Safety Data

• Hazardous Substances Data: 54276-22-1(Hazardous Substances Data)

Usage

Uses

(+)-15-epi-Cloprostenol is a synthetic structural analog of natural prostaglandins PGF2α, and PGE2. (+)-15-epi-Cloprostenol is a chloraryloxy prostaglandin.

Upstream product

• 53872-62-1 [3aα,4α(E),5β,6aα]-(+/-)-4-[4-(3-chlorophenoxy)-3-oxo-1-butenyl]-hexahydro-5-hydroxy-2H-cyclopenta[b]-furan-2-one 
• 41723-91-5 4-carboxybutyliden triphenylphosphorane sodium 
• 89560-44-1 (3aR,4R,5R,6aS)-4-[(E)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-hexahydro-cyclopenta[b]furan-2,5-diol 
• 53872-62-1 Cloprostenol 
• 62961-72-2 Corey aldehyde 

Downstream Products

• 206555-98-8 cloprostenol 
• 54276-21-0 (+)-cloprostenol 

Relevant articles and documents

Synthesizing method of optical pure cloprostenol

The invention relates to the technical field of medicine preparation, in particular to a synthesizing method of optical pure cloprostenol. The synthesizing method comprises the steps: levogyration corey lactone diol is adopted as a raw material and subjec

PROSTANOIDS. XIX. THE SYNTHESIS OF 14C-LABELED CLOPROSTENOL

A 1:3400 mixture of 2-14C-labelled methyl bromoacetate with the nonradioactive ester gave labelled dimethoxy-2-oxo-3-(m-chlorophenoxy)phosphonate which was used for the synthesis of 16-14C-labelled cloprostenol by the Corey strategy.