543690-37-5

Basic information

• Product Name: 1H-Pyrrolizine-1,2-diol,hexahydro-,(1R,2R,7aR)-(9CI)
• Synonyms: 1H-Pyrrolizine-1,2-diol,hexahydro-,(1R,2R,7aR)-(9CI)
• CAS NO: 543690-37-5
• Molecular Formula: C7H13NO2
• Molecular Weight: 0
• Product Categories: AMINETERTIARY
• Mol File: 543690-37-5.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolizine-1,2-diol,hexahydro-,(1R,2R,7aR)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolizine-1,2-diol,hexahydro-,(1R,2R,7aR)-(9CI)(543690-37-5)
• EPA Substance Registry System: 1H-Pyrrolizine-1,2-diol,hexahydro-,(1R,2R,7aR)-(9CI)(543690-37-5)

Safety Data

• Hazardous Substances Data: 543690-37-5(Hazardous Substances Data)

Upstream product

• 155934-28-4 (1S,2R,7aR)-1,2-Di-O-(methanesulfonyl)-1,2-dihydroxypyrrolizidine 
• 18819-89-1 tetrabutylammonium benzoate 
• 141293-15-4 (1'S,2R,4''R)-2-[(2,2-dimethyl-[1,3]dioxolan-4-yl)hydroxymethyl]-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylic acid tert-butyl ester 
• 141293-21-2 (1'S,4''R,5R)-1-(tert-butoxycarbonyl)-5-[(2,2-dimethyl-1,3-dioxolan-4-yl)hydroxymethyl]pyrrolidin-2-one 
• 155934-26-2 2,3-Dideoxy-D-arabino-heptono-1,4-lactam 
• 155934-27-3 5,6,7-Tri-O-(methanesulfonyl)-2,3-dideoxy-D-arabino-heptono-1,4-lactam 
• 155934-35-3 (1R,2S,7aR)-1,2-Di-O-(methanesulfonyl)-1,2-dihydroxypyrrolizidine 
• 156038-81-2 2,3-Dideoxy-L-ribo-heptono-1,4-lactam 
• 141393-87-5 4-<(tert-butoxycarbonyl)amino>-6,7-O-isopropylidene-2,3,4-trideoxy-L-arabino-hept-2-enonic acid 1,4-lactam 
• 156038-79-8 N-(tert-Butoxycarbonyl)-6,7-O-isopropylidene-2,3-dideoxy-L-ribo-hept-2-enono-1,4-lactam 
• 156038-83-4 5,6,7-Tri-O-(methanesulfonyl)-2,3-dideoxy-L-ribo-heptono-1,4-lactam 
• 155934-33-1 (1S,2R,7aS)-1,2-Di-O-(methanesulfonyl)-1,2-dihydroxypyrrolizidine 
• 141393-83-1 (4S,5S,6R)-N-(tert-butoxycarbonyl)-6,7-O-isopropylidene-2,3-dideoxy-hept-2-enono-1,4-lactam 
• 156038-77-6 2,3-Dideoxy-D-ribo-heptono-1,4-lactam 

Relevant articles and documents

Total Synthesis of All Four Isomers of cis-1,2-Dihydroxypyrrolizidine

-

A stereoselective approach to indolizidine and pyrrolizidine alkaloids: Total synthesis of (-)-lentiginosine, (-)-epi-lentiginosine and (-)-dihydroxypyrrolizidine

A simple and highly efficient approach to hydroxylated pyrrolizidine and indolizidine is developed from an aldehyde as a starting material using organocatalytic and asymmetric dihydroxylation reactions as key steps. Its application to the total synthesis of (-)-lentiginosine, (-)-epi-1,2- lentiginosine and (-)-dihydroxypyrrolizidine is also reported. the Partner Organisations 2014.

A facile synthesis of lentiginosine analogues based on a highly regio- and diastereoselective allylic amination using chlorosulfonyl isocyanate

The concise synthesis of the lentiginosine analogues pyrrolidine alkaloid 2 and pyrroloazepine alkaloid 3 has been achieved from, inexpensive and. readily available D-lyxose. The key steps in the synthesis included, regio- and diastereoselective amination