54489-25-7

Basic information

• Product Name: 3-Chloro-5-isoxazoleacetic acid
• Synonyms: 3-Chloro-5-isoxazoleacetic acid;5-Isoxazoleaceticacid,3-chloro-(9CI)
• CAS NO: 54489-25-7
• Molecular Formula: C₅H₄ClNO₃
• Molecular Weight: 161.54316
• Product Categories: OXAZOLE
• Mol File: 54489-25-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Chloro-5-isoxazoleacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-5-isoxazoleacetic acid(54489-25-7)
• EPA Substance Registry System: 3-Chloro-5-isoxazoleacetic acid(54489-25-7)

Safety Data

• Hazardous Substances Data: 54489-25-7(Hazardous Substances Data)

Upstream product

• 1027540-64-2 3-Chloro-5-((E)-2-isocyanato-vinyl)-isoxazole 
• 109627-62-5 (E/Z)-(3-Chloroisoxazol-5-yl)acetaldehyde Oxime 
• 1027597-41-6 (E)-2-(3-Chloro-isoxazol-5-yl)-vinylamine 
• 109627-63-6 (3-Chloro-isoxazol-5-yl)-acetonitrile 

Downstream Products

• 140156-90-7 1-{3-[2-(3-Chloro-isoxazol-5-yl)-acetylamino]-2-oxo-azetidin-1-yl}-cyclohexanecarboxylic acid benzyl ester 
• 124876-31-9 (6R,7R)-3-(2-Benzylsulfanyl-5,5-dimethyl-5H-imidazol-4-ylsulfanylmethyl)-7-[2-(3-chloro-isoxazol-5-yl)-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Relevant articles and documents

Synthesis of Some New Isoxazolylacetic Acid Derivatives

(3-Chloroisoxazol-5-yl)acetic acid 1, a known acylating agent, useful for the synthesis of semi-synthetic cephalosporins was synthesized by a new route.Several α-substituted 3-chloroisoxazolylacetic acids 9a,b; 10a,b and 15, potential acylating agents for semi-synthetic β-lactams, were also prepared.The (E)- and (Z)-3-chloro-α-methoxyiminoisoxazol-5-ylacetic acids 10a,b were separated and their structures unambiguously determined by 1H NMR spectroscopic and X-ray measurements.