54596-70-2

Basic information

• Product Name: 2-[(4-methylpentan-2-yl)amino]ethanol
• CAS NO: 54596-70-2
• Molecular Formula: C₈H₁₉NO
• Molecular Weight: 145.2426
• Mol File: 54596-70-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 224.8°C at 760 mmHg
• Flash Point: 66.8°C
• Density: 0.866g/cm³
• Vapor Pressure: 0.0179mmHg at 25°C
• Refractive Index: 1.439
• CAS DataBase Reference: 2-[(4-methylpentan-2-yl)amino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-methylpentan-2-yl)amino]ethanol(54596-70-2)
• EPA Substance Registry System: 2-[(4-methylpentan-2-yl)amino]ethanol(54596-70-2)

Safety Data

• Hazardous Substances Data: 54596-70-2(Hazardous Substances Data)

Usage

Type of compound

Alcohol amine compound.

Physical state

Colorless liquid.

Odor

Strong ammonia-like odor.

Usage

Commonly used as a solvent and a catalyst in various chemical reactions.

Applications

Production of pharmaceuticals, pesticides, surfactants, manufacturing of rubber and plastics, and as an intermediate in the synthesis of organic compounds.

Hazard classification

Considered to be a hazardous chemical.

Handling precautions

Should be handled with care due to potential health and environmental risks.

Upstream product

• 141-43-5 ethanolamine 
• 108-10-1 4-methyl-2-pentanone 

Relevant articles and documents

Efficient preparation of secondary aminoalcohols through a Ti(IV) reductive amination procedure. Application to the synthesis and antibacterial evaluation of new 3β-N-[hydroxyalkyl]aminosteroid derivatives

An efficient method for the synthesis of various secondary aminoalcohols through a titanium(IV) isopropoxide-mediated reductive amination reaction of ketones is reported. Thus, different ketones gave the expected products in moderate to excellent yields up to 89% in numerous cases. A series of 3β-N-[hydroxyalkyl]aminosteroid derivatives were prepared according to this methodology and evaluated for their in vitro antimicrobial properties against human pathogens. All the compounds showed moderate to excellent activities against Gram-positive bacteria exhibiting similar results against Staphylococcus aureus and Streptococcus faecalis with Minimum Inhibitory Concentrations (MICs) varying from 3.12 to 25 μg/mL. No significant antibacterial activities are encountered against Gram-negative bacteria.