54669-76-0

Basic information

• Product Name: Cyclopentanone, 2-(2-oxo-2-phenylethyl)-
• CAS NO: 54669-76-0
• Molecular Formula: C13H14O2
• Molecular Weight: 202.253
• Mol File: 54669-76-0.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Cyclopentanone, 2-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanone, 2-(2-oxo-2-phenylethyl)-(54669-76-0)
• EPA Substance Registry System: Cyclopentanone, 2-(2-oxo-2-phenylethyl)-(54669-76-0)

Safety Data

• Hazardous Substances Data: 54669-76-0(Hazardous Substances Data)

Upstream product

• 17851-96-6 2-Tributylstannyl-cyclopentanon 
• 100-42-5 styrene 
• 120-92-3 cyclopentanone 
• 1310823-58-5 (E)-1-phenyl-2-(2-(1-phenylethylidene)cyclopentyl)ethanone 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 
• 120312-58-5 C₁₄H₁₂IO⁽¹⁺⁾*BF₄^(1-) 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 66324-10-5 tert-butyldimethyl(1-phenylvinyloxy)silane 
• 1056246-36-6 2-bromocyclopentanone 
• 694-28-0 2-chlorocyclopentanone 
• 7766-48-5 1-iodo-4-pentene 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 
• 874115-62-5 8-oxo-8-phenyloct-6-enal 

Downstream Products

• 137622-17-4 1-(1-Hydroxy-2-phenacylcyclopentyl)phosphonous acid 
• 96756-89-7 4-(2-Phenyl-5,6-dihydro-4H-cyclopenta[b]pyrrol-1-yl)-phenol 
• 54669-66-8 2-hydroxy-5-(2-phenyl-5,6-dihydro-4H-cyclopenta[b]pyrrol-1-yl)-benzoic acid 
• 79379-48-9 4,5-dihydro-2-phenylcyclopentapyrrole 
• 96756-90-0 2-Phenyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1,4,5,6-tetrahydro-cyclopenta[b]pyrrole 
• 34595-83-0 3-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridazine 

Relevant articles and documents

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

Reported herein is a visible-light-mediated radical approach to the α-alkylation of ketones. This method exploits the ability of a nucleophilic organocatalyst to generate radicals upon SN2-based activation of alkyl halides and blue light irradiation. The resulting open-shell intermediates are then intercepted by weakly nucleophilic silyl enol ethers, which would be unable to directly attack the alkyl halides through a traditional two-electron path. The mild reaction conditions allowed functionalization of the α position of ketones with functional groups that are not compatible with classical anionic strategies. In addition, the redox-neutral nature of this process makes it compatible with a cinchona-based primary amine catalyst, which was used to develop a rare example of enantioselective organocatalytic radical α-alkylation of ketones.

The synthesis of cycloalka[: B] furans via an Au(i)-catalyzed tandem reaction of 3-yne-1,2-diols

An Au(i)-catalyzed cyclization/1,2-rearrangement/aromatization cascade of 3-yne-1,2-diols has been successfully realized. This reaction not only provides a new and efficient strategy for the synthesis of substituted cycloalka[b]furan compounds as well as their derivatives, but might also facilitate related biological studies.

Catalyst-free formation of 1,4-diketones by addition of silyl enolates to oxyallyl zwitterions in situ generated from α-haloketones

Reported here is the exclusive formation of 1,4-diketones by the uncatalyzed reaction of silyl enolates and α-haloketones. Enolates I are inherently more likely to react with α-haloketones II at the carbonyl carbon to produce halohydrin derivatives III or