54675-49-9

Basic information

• Product Name: 8-Bromo-3-nitroquinoline-2,4-diol
• Synonyms: 8-Bromo-3-nitroquinoline-2,4-diol;8-Bromo-4-hydroxy-3-nitro-2(1H)-quinolinone
• CAS NO: 54675-49-9
• Molecular Formula: C9H5BrN2O4
• Molecular Weight: 285.051
• Mol File: 54675-49-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 2.02
• CAS DataBase Reference: 8-Bromo-3-nitroquinoline-2,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Bromo-3-nitroquinoline-2,4-diol(54675-49-9)
• EPA Substance Registry System: 8-Bromo-3-nitroquinoline-2,4-diol(54675-49-9)

Safety Data

• Hazardous Substances Data: 54675-49-9(Hazardous Substances Data)

Usage

General Description

8-Bromo-3-nitroquinoline-2,4-diol is a chemical compound with the molecular formula C9H5BrN2O4. It is a synthetic organic compound with potential antineoplastic and radiosensitizing activities. 8-Bromo-3-nitroquinoline-2,4-diol has been studied for its potential use in cancer therapy, as it has shown to be effective in reducing the viability of cancer cells and sensitizing them to radiation treatment. Additionally, 8-Bromo-3-nitroquinoline-2,4-diol has also been investigated for its potential use in the development of new anticancer drugs. It is a research chemical and its full potential for medical use is still being explored.

Upstream product

• 54675-27-3 8-bromo-4-hydroxy-2-quinolone 

Relevant articles and documents

ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES

Aryl substituted imidazoquinoline compounds, according to formula I, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing w or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral., and neoplastic, are disclosed. formula (I): wherein: R is selected from the group consisting of alkyl, alkoxy, hydroxy, and trifluoromethyl;. N is 0 or 1; R3 is selected from the group consisting of: -Z-Ar,-Z-Ar’-Y-R4, -Z-Ar’-X-Y-R4, Z-Ar’-R5, and-Z-Ar'-X-R5; Ar is selected from the group consisting of aryl and heteroaryl both of which can be unsubstituted or can be substituted by one or more substituents independently selected from the group consisting of alkyl, alkenyl, alkoxy, methylenedioxy, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, hydroxyalkyl, mercapto, cyano, carboxy, formyl, aryl, aryloxy, arylalkoxy, heteroaryl, heteroaryloxy, heteroarylalkoxy; heterocyctyl, heterocyclylalkyl, amino, alkylamino, and dialkylamino.