54714-49-7

Basic information

• Product Name: DIISOPROPYLAMINOACETONITRILE
• Synonyms: DIISOPROPYLAMINOACETONITRILE;Nsc26718
• CAS NO: 54714-49-7
• Molecular Formula: C₈H₁₆N₂
• Molecular Weight: 140.23
• Mol File: 54714-49-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 61°C/3/ 10mm
• Flash Point: 67.4 °C
• Appearance: /
• Density: 0.865 g/cm³
• Vapor Pressure: 0.26mmHg at 25°C
• Refractive Index: 1.439
• PKA: 6.39±0.28(Predicted)
• CAS DataBase Reference: DIISOPROPYLAMINOACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: DIISOPROPYLAMINOACETONITRILE(54714-49-7)
• EPA Substance Registry System: DIISOPROPYLAMINOACETONITRILE(54714-49-7)

Safety Data

• Hazard Codes: C
• HazardClass: CORROSIVE
• Hazardous Substances Data: 54714-49-7(Hazardous Substances Data)

Usage

General Description

DIISOPROPYLAMINOACETONITRILE is a chemical compound with the molecular formula C8H17N. It is commonly used as a reagent in organic synthesis, specifically in the preparation of various pharmaceuticals and agrochemicals. This chemical is known for its ability to function as a strong base and as a nucleophile, making it useful in a wide range of chemical reactions. DIISOPROPYLAMINOACETONITRILE is a clear, colorless liquid with a faint odor, and it is considered to be hazardous, particularly in its concentrated form, due to its potential to cause irritation to the skin, eyes, and respiratory system. It is important to handle and store this chemical with care, following proper safety protocols and regulations.

InChI:InChI=1/C8H16N2/c1-7(2)10(6-5-9)8(3)4/h7-8H,6H2,1-4H3

Upstream product

• 10342-97-9 N,N-diisopropylmethylamine 
• 143-33-9 sodium cyanide 
• 50-00-0 formaldehyd 
• 151-50-8 potassium cyanide 
• 108-18-9 diisopropylamine 
• 590-17-0 cyanomethyl bromide 
• 7677-24-9 trimethylsilyl cyanide 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 406913-26-6 N,N-diisopropyl-2-cyanothioacetamide 
• 121-05-1 N',N'-diisopropyl-ethane-1,2-diamine 

Relevant articles and documents

Synthesizing method of N,N-diisoprylamino ethylamine

The invention discloses a synthesizing method of N,N-diisoprylamino ethylamine. The synthesizing method comprises the following steps of using diisopropylamine and chloroacetonitrile as initial raw materials, and performing aminolysis reaction and reduction reaction, so as to synthesize the N,N-diisoprylamino ethylamine. The synthesizing method has the advantages that the technology route is advanced, the technology condition is reasonable, the cost of raw materials is low, the obtaining is easy, the reaction condition is mild, the operation is simple and safe, the atom economy is high, the production cost is low, the amount of three wastes (waste gas, waste water and industrial residue) is small, the synthesizing method is suitable for industrialized production, and the larger implementing value and social and economical benefits are realized.

A Widely applicable regioselective aerobic α-cyanation of tertiary amines heterogeneously catalyzed by manganese oxides

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C-C - CONNECTIVE SYNTHESIS OF α-DIALKYLAMINO - KETONES FROM ALDEHYDES AND SEC.-AMINES

A simple and efficient 3 - step synthesis of α-dialkylamino - ketones 3 starting from aldehydes and sec.-amines is described.The unsymmetrically aminoketones are obtained as pure regioisomers via reaction of metalated α-aminonitriles 1 with aldehydes, followed by thermal HCN-elimination/tautomerization.