54745-74-3

Basic information

• Product Name: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE
• Synonyms: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE;8-Oxa-3-azabicyclooctaneHCl;8-Oxa-3-azabicyclo[3.2.1]octane monohydrochloride;8-Oxa-3-azabicyclo[3.2.1]octane, HCl;8-OXA-3-AZABICYCLO[3.2.1];8-Oxa-3-azabicyclo[3.2.1]octane,hydrochloride (1:1);8-oxa-3-azabicyclo[3.2.1]octane HCl salt
• CAS NO: 54745-74-3
• Molecular Formula: C₆H₁₁NO*ClH
• Molecular Weight: 149.62
• Product Categories: Heterocycles series;Fused Ring Systems
• Mol File: 54745-74-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 197-199 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(54745-74-3)
• EPA Substance Registry System: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(54745-74-3)

Safety Data

• Hazardous Substances Data: 54745-74-3(Hazardous Substances Data)

Usage

Uses

8-Oxa-3-azabicyclo[3.2.1]octane hydrochloride is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

InChI:InChI=1/C6H11NO.ClH/c1-2-6-4-7-3-5(1)8-6;/h5-7H,1-4H2;1H

Upstream product

• 3238-40-2 furan-2,5-dicarboxylic acid 
• 54745-75-4 3-benzyl-8-oxa-3-aza-bicyclo[3.2.1]octane 

Downstream Products

• 54745-77-6 3-phenylacetyl-8-oxa-3-aza-bicyclo[3.2.1]octane 
• 1144075-91-1 1-(1-benzyl-piperidin-4-yl)-6-chloro-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1144080-11-4 6-chloro-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1127238-02-1 13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-6-[1-methyl-4-(8-oxa-3-azabicyclo[3.2.1]-oct-3-ylcarbonyl)-1H-pyrazol-5-yl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1127238-34-9 13-cyclohexyl-6-[1-ethyl-3-methyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-ylcarbonyl)-1H-pyrazol-5-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 

Relevant articles and documents

Concise syntheses of bridged morpholines

Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.

8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals

Disclosed are compounds, having the following general formula, which are useful as analgesics in living animals. SPC1 Wherein R is a radical selected from the group consisting of aralkyl, aryl, aminoalkyl, arylalkanoyl, heteroaroyl, alkoxy substituted aroyl, alkenyl (C2 to C4), halogen substituted aralkyl, guanadinoalkyl, halogen substituted aroyl, alkyl substituted aroyl, halogen substituted arylalkanoyl, hexahydrobenzoyl, arylalkenoyl, o- or p-alkyl substituted phenylalkanoyl, alkyl substituted naphthylalkanoyl, alkanoyl (C3 to C20), haloalkyl substituted aroyl, alkoxy substituted aralkyl, heteroaralkyl, anilinocarbonyl, adamantanecarbonyl, arylsulfonyl, carboxyl substituted aroyl, hydroxyl substituted aroyl, alkanoyloxy substituted aroyl, arylglyoxylyl, alicyclic, arylene dicarbonyl-8-oxa-3-azabicyclo(3.2.1)octane, alkylene-8-oxa-3-azabicyclo (3.2.1)octane, alkylene dicarbonyl-8-oxa-3-azabicyclo(3.2.1)octane, and the pharmacologically acceptable acid addition salts thereof.