548783-71-7

Basic information

• Product Name: FEXOFENADINE-D6
• Synonyms: 4-[1-Hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-α,α-(diMethyl-d6)benzeneacetic Acid;4-[4-[4-(HydroxydiphenylMethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α- (diMethyl-d6)phenylacetic Acid;Carboxyterfenadine-d6;MDL 16455-d6;Terfenadine-d6 Acid Metabolite;Terfenadine-d6 Carboxylate
• CAS NO: 548783-71-7
• Molecular Formula: C32H33D6NO4
• Molecular Weight: 507.7
• Product Categories: Isotope Labeled Compounds;Metabolites;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals
• Mol File: 548783-71-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 193-196°C
• Boiling Point: 697.261°C at 760 mmHg
• Flash Point: 375.49°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: Amber Vial, -20°C Freezer
• CAS DataBase Reference: FEXOFENADINE-D6(CAS DataBase Reference)
• NIST Chemistry Reference: FEXOFENADINE-D6(548783-71-7)
• EPA Substance Registry System: FEXOFENADINE-D6(548783-71-7)

Safety Data

• Hazardous Substances Data: 548783-71-7(Hazardous Substances Data)

Usage

Description

FEXOFENADINE-D6 is a deuterated analog of Fexofenadine, which is the active metabolite of Terfenadine, a H1-histamine receptor antagonist. It is a white solid and is commonly used as a labeled reference compound for analytical purposes in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
FEXOFENADINE-D6 is used as a labeled reference compound for [application reason] in the pharmaceutical industry. It is utilized in the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), to ensure the accurate quantification and identification of Fexofenadine in various samples, including pharmaceutical formulations and biological matrices.
Used in Research and Development:
FEXOFENADINE-D6 is used as a research tool for [application reason] in the field of drug discovery and development. It aids researchers in understanding the pharmacokinetics, metabolism, and mechanism of action of Fexofenadine, which can be crucial for the development of new drugs with similar or improved therapeutic properties.
Used in Quality Control:
FEXOFENADINE-D6 is used as a quality control standard for [application reason] in the pharmaceutical industry. It helps ensure the quality, purity, and potency of Fexofenadine-containing products by providing a reference for comparison during the manufacturing process and product testing.
Used in Toxicology Studies:
FEXOFENADINE-D6 is used as an internal standard for [application reason] in toxicology studies. It assists in the accurate measurement of Fexofenadine and its metabolites in biological samples, which is essential for understanding the drug's safety profile and potential toxic effects.

InChI:InChI=1/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)/i1D3,2D3