54879-74-2

Basic information

• Product Name: 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE
• Synonyms: 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE
• CAS NO: 54879-74-2
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.24
• Mol File: 54879-74-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE(54879-74-2)
• EPA Substance Registry System: 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE(54879-74-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 54879-74-2(Hazardous Substances Data)

Usage

General Description

2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE is a chemical compound with a molecular formula C11H15NO2. It is a derivative of 2-dimethoxyaminoethylamine and is commonly used as a reagent in organic synthesis processes. 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE is known for its applications in the production of various pharmaceutical and agrochemical products. It has also been studied for its potential use in the treatment of neurological disorders and as a precursor in the synthesis of other complex organic molecules. Additionally, 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE is considered to be a useful building block in the development of new chemical compounds for industrial and research purposes.

Upstream product

• 100-52-7 benzaldehyde 
• 22483-09-6 2,2-dimethoxyethylamine 

Downstream Products

• 54879-88-8 N-benzyl-2,2-dimethoxyethylamine 
• 166947-03-1 benzyl benzyl(2-oxoethyl)carbamate 
• 307002-13-7 benzyl (benzyl)(2,2-dimethoxyethyl)carbamate 
• 307002-62-6 benzyl (benzyl){2-[2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl]-2-(1H-indol-3-yl)ethyl}carbamate 
• 307002-18-2 ethyl hydrogen 2-{2-[(benzyl)(benzyloxycarbonyl)amino]-1-(1H-indol-3-yl)ethyl}malonate 
• 307002-19-3 ethyl 4-[(benzyl)(benzyloxycarbonyl)amino]-2-[(benzyloxycarbonyl)amino]-3-(1H-indol-3-yl)butyrate 
• 23269-10-5 1-benzyl-1H-imidazole-2-thione 
• 1344689-02-6 C₂₂H₂₉NO₅ 
• 1344689-05-9 C₂₀H₂₁NO₃ 
• 1344689-07-1 C₂₁H₂₁NO₄ 
• 1344689-09-3 C₁₈H₁₅NO₂ 
• 1344689-12-8 C₁₈H₁₃NO₃ 
• 1344688-58-9 C₁₈H₁₃NO₄ 
• 1456807-34-3 1-(4-benzyl-6-methoxymorpholin-2-yl)ethanol 

Relevant articles and documents

Six-Step Gram-Scale Synthesis of the Human Immunodeficiency Virus Integrase Inhibitor Dolutegravir Sodium

A short and practical synthesis for preparing the active pharmaceutical ingredient dolutegravir sodium was developed. The convergent strategy starts from (R)-3-amino-1-butanol and establishes the BC ring system in a 76% isolated yield over four steps. Ring A was constructed by a one-pot 1,4-addition to diethyl-(2E/Z)-2-(ethoxymethylidene)-3-oxobutandioate and subsequent MgBr2·OEt2-mediated regioselective cyclization. Amide formation with 2,4-difluorobenzylamine was either performed from the free carboxylic acid or through aminolysis of the corresponding ethyl ester. Final salt formation afforded dolutegravir sodium in a 48-51% isolated yield (HPLC purity of 99.7-99.9%) over six linear steps.

Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors

Through high throughput screening and subsequent hit identification and optimization, we synthesized a series of 1-arylcarbonyl-6,7- dimethoxyisoquinoline derivatives as the first reported potent and reversible GFAT inhibitors. SAR studies of this class o

Multisubstrate inhibitors of dopamine β-hydroxylase. 2. Structure-activity relationships at the phenethylamine binding site

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