54924-78-6

Basic information

• Product Name: 5-bromo-2-ethoxybenzamide
• Synonyms: 5-Bromo-2-ethoxybenzamide; benzamide, 5-bromo-2-ethoxy-
• CAS NO: 54924-78-6
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.0852
• Mol File: 54924-78-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 317.6°C at 760 mmHg
• Flash Point: 145.9°C
• Density: 1.48g/cm³
• Vapor Pressure: 0.000382mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 5-bromo-2-ethoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-ethoxybenzamide(54924-78-6)
• EPA Substance Registry System: 5-bromo-2-ethoxybenzamide(54924-78-6)

Safety Data

• Hazardous Substances Data: 54924-78-6(Hazardous Substances Data)

Upstream product

• 74-96-4 ethyl bromide 
• 6329-74-4 5-bromo-2-hydroxybenzamide 
• 64-17-5 ethanol 
• 170492-50-9 2,5-dibromobenzamide 
• 16602-11-2 2-Aethoxy-5-brom-acetophenon 
• 29643-62-7 2-ethoxy-1-ethybenzene 

Relevant articles and documents

Copper-Catalyzed Self-Condensation of Benzamide: Domino Reactions towards Quinazolinones

We herein report a simple and highly efficient microwave-assisted, copper-catalyzed and ligand-free synthetic method for 2-substituted 4(3H)-quinazolinones as domino reaction. This reaction proceeds via self-condensation of substrate (2-bromo/iodo benzamide) in the presence of a strong base and copper catalyst. The substituted quinazolinones were obtained in one-pot reaction by intramolecular cyclization (condensation) via Ullmann–type intermediate. Both the intermediates and quinazolinones were obtained in good yield and can be further used as building blocks for developing the potential novel drug-like compounds.

REACTION OF SALICYCLIC ACID DERIVATIVES WITH ACETYLENE

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