54997-91-0

Basic information

• Product Name: Benzenesulfonyl chloride, 4-octyl-
• Synonyms: p-octylbenzenesulfonyl chloride;Benzenesulfonyl chloride,4-octyl;4-Oktylbenzolsulfonylchlorid;4-n-octylbenzenesulfonyl chloride;p-n-Octylbenzolsulfonylchlorid
• CAS NO: 54997-91-0
• Molecular Formula: C14H21ClO2S
• Molecular Weight: 288.839
• Mol File: 54997-91-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl chloride, 4-octyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl chloride, 4-octyl-(54997-91-0)
• EPA Substance Registry System: Benzenesulfonyl chloride, 4-octyl-(54997-91-0)

Safety Data

• Hazardous Substances Data: 54997-91-0(Hazardous Substances Data)

Upstream product

• 6149-03-7 sodium p-(n-octyl)benzene sulphonate 
• 72978-95-1 8-chloro-octan-2-one 
• 71-43-2 benzene 
• 2189-60-8 Octylbenzene 

Downstream Products

• 4527-48-4 p-n-octylbenzenethiol 
• 54997-22-7 2-(4-n-Octylphenylthio)benzylalkohol 
• 54997-26-1 C₂₁H₂₇ClS 
• 54997-19-2 2-(4-Octyl-phenylsulfanyl)-benzoic acid 
• 54997-34-1 [2-(4-Octyl-phenylsulfanyl)-phenyl]-acetic acid 
• 1191951-80-0 4-octyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1352144-07-0 (R)-(4'-octylbenzenesulfonylamino)-tetrahydropyridin-2-one 
• 1352144-05-8 (S)-3-(4'-octylbenzenesulfonylamino)-azepan-2-one 
• 1352144-06-9 (S)-3-(4'-octylbenzenesulfonylamino)-tetrahydropyridin-2-one 

Relevant articles and documents

Expanding the structural diversity of hydrophobic ionic liquids: physicochemical properties and toxicity of Gemini ionic liquids

Ionic liquids (ILs) have been labeled as a promising green alternative to traditional materials; however, many ILs have been discovered to be toxic, especially hydrophobic ILs (HILs). HILs are limited in their structural diversity as most are composed of heteroaromatic cations with long alkyl chains and paired with [BF4], [PF6], or [NTf2] anions. This study aims to diversify HILs by synthesizing two sets of HILs with unique cations and anions. The first set of HILs contain cholinium- and dicholinium-based cations paired with the [NTf2] anion. The [DC-ether] cation is identified as a promising cation and is paired with an array of asymmetric bis(sulfonyl)amide anions to form the second set of HILs. In total, twenty HILs are synthesized. Each HIL is characterized using traditional physicochemical techniques and is evaluted for toxicity usingin vitroandin vivomethods.

Effects of lipophilicity, protecting group and stereochemistry on the antimalarial activity of carbohydrate-derived thiochromans

A series of novel carbohydrate-derived thiochromans has been successfully synthesized in order to investigate the influence of alkyl substituents on the aromatic ring of the thiophenol moiety in addition to the effect of protecting groups and stereochemistry on the sugar component of the target molecules. Results from the evaluation of the thiochromans for their antimalarial activity against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum suggest that the presence of short chain alkyl substituents, a benzyl ether protecting group and equatorial orientation of the C-4 substituent on the sugar moiety are crucial structural features that impart high antimalarial activity.

SMALL MOLECULE INHIBITORS OF THE PLECKSTRIN HOMOLOGY DOMAIN AND METHODS FOR USING SAME

Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.