550998-59-9

Basic information

• Product Name: 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID
• Synonyms: 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID;7-Bromo-2-benzofurancarboxylic acid;2-Benzofurancarboxylic acid, 7-bromo-
• CAS NO: 550998-59-9
• Molecular Formula: C₉H₅BrO₃
• Molecular Weight: 241.04
• Mol File: 550998-59-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 370.9 °C at 760 mmHg
• Flash Point: 178.1 °C
• Appearance: /
• Density: 1.784 g/cm³
• Vapor Pressure: 3.71E-06mmHg at 25°C
• Refractive Index: 1.679
• Storage Temp.: 2-8°C
• PKA: 2.90±0.30(Predicted)
• CAS DataBase Reference: 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID(550998-59-9)
• EPA Substance Registry System: 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID(550998-59-9)

Safety Data

• Hazardous Substances Data: 550998-59-9(Hazardous Substances Data)

Usage

General Description

7-Bromo-1-benzofuran-2-carboxylic acid is a chemical compound with the molecular formula C9H5BrO3. It is a carboxylic acid derivative of benzofuran, containing a bromine atom at the 7th position. 7-Bromo-1-benzofuran-2-carboxylicacid has a variety of potential applications in the pharmaceutical and chemical industries due to its unique structure and properties. It can be used as a building block in the synthesis of various drugs and organic compounds. Additionally, it has shown promise in research for its potential biological activities, including anti-inflammatory and anti-cancer properties. Its distinctive structure makes it a valuable tool for the development of new and innovative molecules.

InChI:InChI=1/C9H5BrO3/c10-6-3-1-2-5-4-7(9(11)12)13-8(5)6/h1-4H,(H,11,12)

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 1829-34-1 2-hydroxy-3-bromobenzaldehyde 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 634905-16-1 7-(2-methoxyphenyl)-1-benzofuran-2-carboxylic acid 
• 634905-03-6 (3R)-1-benzyl-3-({[7-(2-methoxyphenyl)-1-benzofuran-2-yl]carbonyl}amino)-1-azoniabicyclo[2.2.2]octane bromide 
• 634904-68-0 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[3-({[2-(dimethylamino)ethyl]amino}-carbonyl)phenyl]-1-benzofuran-2-carboxamide hydrochloride 
• 634905-02-5 (3R)-3-({[7-(2-methoxyphenyl)-1-benzofuran-2-yl]carbonyl}amino)-1-methyl-1-azoniabicyclo[2.2.2]octane chloride 
• 634904-70-4 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(3-{[(2-methoxyethyl)(methyl)amino]carbonyl}phenyl)-1-benzofuran-2-carboxamide hydrochloride 
• 634904-64-6 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(3-{[ethyl(methyl)amino]carbonyl}phenyl)-1-benzofuran-2-carboxamide hydrochloride 
• 788820-67-7 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[3-({[2-(dimethylamino)ethyl]amino}-carbonyl)phenyl]-1-benzofuran-2-carboxamide 
• 747408-41-9 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(3-{[(2-methoxyethyl)(methyl)amino]carbonyl}phenyl)-1-benzofuran-2-carboxamide 
• 740081-61-2 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(3-{[ethyl(methyl)amino]carbonyl}phenyl)-1-benzofuran-2-carboxamide 
• 634905-05-8 7-(2-methoxyphenyl)-N-[(3R)-1-oxido-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-2-carboxamide 
• 634904-94-2 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-{3-[(cyclopentylcarbonyl)amino]phenyl}-1-benzofuran-2-carboxamide hydrochloride 
• 634904-67-9 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[3-(1-piperidinylcarbonyl)phenyl]-1-benzofuran-2-carboxamide hydrochloride 
• 634904-71-5 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(3-{[(3-ethoxypropyl)amino]carbonyl}phenyl)-1-benzofuran-2-carboxamide hydrochloride 
• 634904-13-5 N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[4-(morpholinylcarbonyl)phenyl]-1-benzofuran-2-carboxamide hydrochloride 

Relevant articles and documents

Compound containing benzo five-membered heterocyclic structure and preparation method and application thereof

The invention relates to the field of medicinal chemistry, and discloses a compound containing a benzo five-membered heterocyclic structure as well as a preparation method and application thereof. The invention also discloses a composition containing the benzo five-membered heterocyclic compound or the pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier, and application of the composition in preparation of PARP-1 and ERK inhibitors. The compound can be used for treating diseases such as tumors.