55211-71-7

Basic information

• Product Name: Ampurine
• CAS NO: 55211-71-7
• Mol File: 55211-71-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ampurine(CAS DataBase Reference)
• NIST Chemistry Reference: Ampurine(55211-71-7)
• EPA Substance Registry System: Ampurine(55211-71-7)

Safety Data

• Hazardous Substances Data: 55211-71-7(Hazardous Substances Data)

Downstream Products

• 77931-49-8 C₁₂H₁₈ClN₈OP 

Relevant articles and documents

Pharmaceutical composition containing 2-dimethylamino-6-diethyleneimidophosphamido-7-methyl-purine

2-Dimethylamino-6-diethyleneimidophosphamido-7-methylpurine having the formula STR1 A method for preparing 2-dimethylamino-6-diethyleneimido-phosphamido-7-methylpurine consisting of treating theo-bromine with heating to the boiling point and subsequently with phosphorus oxychloride and phosphorus pentachloride. The prepared 2,6-dichloro-7-methylpurine is heated to 50° - 60° C in an aqueous solution of ammonia and the resulting 2-chloro-6-amino-7-methylpurine is reacted, with heating, with a aqueous solution of dimethylamine. The obtained 2-dimethylamino-6-amino-7-methylpurine is reacted, at the boiling point, with either phosphorus oxychloride, or phosphorus pentachloride and formic acid. The resulting 2-dimethylamino-7-methylpurinyl-6-aminophosphoric dichloroanhydride is then treated with ethyleneimine in a medium of an organic solvent in the presence of an acceptor of hydrogen chloride, and the final product is then isolated. A preparation for treating malignant tumors of the haemopoietic system, containing 2-dimethylamino-6-diethyleneimidophosphamido-7-methylpurine as the active principle is provided.