5524-30-1 Usage
Description
(2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile is a complex organic molecule with a molecular formula C23H21N5O2. It features a benzimidazole ring, a piperidine ring, a nitrophenyl group, and a nitrile group. (2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile possesses potential bioactivity and is of interest in pharmaceutical research and drug development. Due to its potential reactivity and toxicity, it is crucial to handle and store this chemical according to safety guidelines and regulations.
Uses
Used in Pharmaceutical Research:
(2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile is used as a research compound for exploring its potential bioactivity and therapeutic applications. Its unique structure, which includes a benzimidazole ring and a nitrophenyl group, may contribute to its interaction with biological targets, making it a candidate for further investigation in drug discovery processes.
Used in Drug Development:
In the field of drug development, (2Z)-2-(6-methyl-1H-benzimidazol-2-yl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-enenitrile serves as a lead compound. Its chemical properties and potential reactivity allow it to be modified and optimized for specific pharmaceutical applications. Researchers can use this compound as a starting point to design new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 5524-30-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,2 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5524-30:
(6*5)+(5*5)+(4*2)+(3*4)+(2*3)+(1*0)=81
81 % 10 = 1
So 5524-30-1 is a valid CAS Registry Number.
5524-30-1Relevant articles and documents
Synthesis and evaluation of carbamate prodrugs of a phenolic compound
Igarashi, Yasushi,Yanagisawa, Erika,Ohshima, Toshihiro,Takeda, Shuichi,Aburada, Masaki,Miyamoto, Ken-Ichi
, p. 328 - 333 (2007/10/03)
A series of carbamates of the phenolic compound 1 were prepared and evaluated in vivo as its prodrug. Each carbamate was orally administered to rats, and plasma concentrations of the parent compound 1 were measured with the passage of time. We judged which carbamate was suitable for the prodrug of 1 from both the AUC value of 1 and absence of the carbamate in plasma. The AUC value of 1 after oral administration of 2b was approximately 40-fold higher than that for an administration of 1, and the bioconversion from 2b to 1 was excellent. As a whole, di-substituted carbamates resulted in higher plasma concentrations of 1 than did mono-substituted ones. However di-substituted carbamates were almost always detected in plasma. As a result, we found that the ethycarbamoyl derivative 2b demonstrates the best prodrug property in this series.
