55387-85-4

Basic information

• Product Name: 2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL
• Synonyms: 3,3-BIS(HYDROXYMETHYL)PROPIONALDEHYDE DIETHYL ACETAL;3,3-DIETHOXY-1,1-BIS(HYDROXYMETHYL)PROPANE;2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL;4,4-DIETHOXY-2-HYDROXYMETHYLBUTANOL;Diethoxyethylpropanediol;2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL 95+%;1,3-Propanediol, 2-(2,2-diethoxyethyl)-;3,3-Bis(hydroxymethyl)propionaldehyde Diethyl Acetal 3,3-Diethoxy-1,1-bis(hydroxymethyl)propane 4,4-Diethoxy-2-hydroxymethylbutanol
• CAS NO: 55387-85-4
• Molecular Formula: C₉H₂₀O₄
• Molecular Weight: 192.25
• Mol File: 55387-85-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 301.09oC at 760 mmHg
• Flash Point: 135.895oC
• Appearance: /
• Density: 1.04
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.4480-1.4520
• CAS DataBase Reference: 2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL(55387-85-4)
• EPA Substance Registry System: 2-(2,2-DIETHOXYETHYL)-1,3-PROPANEDIOL(55387-85-4)

Safety Data

• Hazardous Substances Data: 55387-85-4(Hazardous Substances Data)

Usage

General Description

The chemical 2-(2,2-diethoxyethyl)-1,3-propanediol, also known as DEEHP, is a diethylene glycol ether derivative that is commonly used as a plasticizer in various polymer applications such as PVC and other resins. It is a clear, colorless liquid with a faint odor, and it is known for its ability to improve flexibility and durability in plastics. DEEHP is also used as a solvent in coatings, adhesives, and other industrial applications. However, it is important to note that DEEHP has been identified as a potential reproductive toxicant and is subject to regulations and restrictions in some countries.

InChI:InChI=1/C9H20O4/c1-3-12-9(13-4-2)5-8(6-10)7-11/h8-11H,3-7H2,1-2H3

Upstream product

• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 105-53-3 diethyl malonate 
• 21339-47-9 diethyl 2-(2,2-diethoxyethyl)malonate 

Downstream Products

• 144461-19-8 (R)-2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate 
• 1300041-64-8 1-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-(3-(2-(dimethylamino)ethyl)-7-imino-3,4-dihydro-[1,4]dioxepino[2,3-f]isoindol-8(2H,7H,9H)-yl)ethanone 
• 851528-70-6 4,4-diethoxy-2-(4-trifluoromethyl-phenoxymethyl)-butan-1-ol 
• 639-97-4 D-apiose 
• 51311-41-2 (4R)-4-(hydroxymethyl)-3-(6-methylheptanoyl)dihydro-furan-2(3H)-one 
• 64190-48-3 (S)-3-methyl-4-butanolide 
• 140193-21-1 C₄₀H₇₄NO₅PS₂ 
• 113897-54-4 C₃₇H₆₈NO₆P 
• 140193-15-3 3-{2-[3-(tert-Butyl-dimethyl-silanyloxy)-2-octadecyloxymethyl-propyl]-[1,3]dithian-2-yl}-cyclohexanone 
• 113897-22-6 2-Octadecyloxymethyl-3-[2-(3-phenyl-propyl)-[1,3]dithian-2-yl]-propan-1-ol 
• 146609-12-3 5(S)-<4-amino-2(1H)-pyrimidinone>tetrahydro-3(R)-furanmethanol 
• 134665-21-7 2,2-Dimethyl-propionic acid (S)-5-(6-benzoylamino-purin-9-yl)-tetrahydro-furan-3-ylmethyl ester 
• 333335-50-5 benzoic acid 5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-ylmethyl ester 
• 333335-54-9 benzoic acid 5-(2-amino-6-chloro-purin-9-yl)-tetrahydro-furan-3-ylmethyl ester 

Relevant articles and documents

Synthesis of acyclic nucleoside derivatives

Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.

New 4-substituted 2-alkoxytetrahydrofuran derivatives

The present invention describes a process to obtain 4-substituted 2--alkoxytetrahydrofuran derivatives of formula I. wherein,-R1 represents an alkyl or phenylalkyl radical; -R2 is hydrogen, C1-C4-acyl or C1