55478-53-0

Basic information

• Product Name: 2-Pyrrolidinecarbonyl chloride, 5-oxo- (9CI)
• Synonyms: 2-Pyrrolidinecarbonyl chloride, 5-oxo- (9CI);5-oxopyrrolidine-2-carbonyl chloride;5-Oxo-2-pyrrolidinecarbonyl chloride
• CAS NO: 55478-53-0
• Molecular Formula: C₅H₆ClNO₂
• Molecular Weight: 147.55964
• Product Categories: ACIDHALIDE
• Mol File: 55478-53-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 71-74 °C (decomp)
• Boiling Point: 82 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.374±0.06 g/cm3(Predicted)
• PKA: 14.33±0.40(Predicted)
• CAS DataBase Reference: 2-Pyrrolidinecarbonyl chloride, 5-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinecarbonyl chloride, 5-oxo- (9CI)(55478-53-0)
• EPA Substance Registry System: 2-Pyrrolidinecarbonyl chloride, 5-oxo- (9CI)(55478-53-0)

Safety Data

• Hazardous Substances Data: 55478-53-0(Hazardous Substances Data)

Upstream product

• 149-87-1 Pyroglutamic acid 
• 98-79-3 L-Pyroglutamic acid 

Downstream Products

• 4931-66-2 methyl 5-oxopyrrolidine-2-carboxylate 
• 5626-52-8 5-oxo-pyrrolidine-2-carboxylic acid amide 
• 149-87-1 Pyroglutamic acid 
• 111556-29-7 5-benzoyl-2-pyrrolidinone 

Relevant articles and documents

Calycosin derivative as well as preparation method and application thereof

The invention relates to a calycosin derivative as well as a preparation method and application thereof, belonging to the field of medicinal chemistry. The calycosin derivative is of a structure A shown in the specification, wherein R1 and R2 are out one

Haem d1: Development of a new coupling procedure leading to the synthesis of isobacteriochlorins

A new approach has been developed for construction of the western and eastern lactams, e.g. 2 and 3, needed for synthesis of isobacteriochlorins. It involves acylation of pyrroles with lactonic acids to form ketones. These are then efficiently converted into the desired lactams by a short sequence of reactions. All the steps are high yielding and simple to carry out.