5560-72-5Relevant articles and documents
One-pot approach to installing eight-membered rings onto indoles
Zhu, Can,Zhang, Xue,Lian, Xiongdong,Ma, Shengming
, p. 7817 - 7820 (2012/09/08)
Ring fusion: The Pd0-catalyzed reaction of 2-allyl-3-iodo-1- tosyl-1H-indoles and propargylic bromides affords dihydrocycloocta[b]indoles (see scheme; M.S.=molecular sieves, TFP=tris(2-furyl)phosphine, Ts=4-toluenemethanesulfonyl), and proceeds
Fischer indole synthesis with organozinc reagents
Haag, Benjamin A.,Zhang, Zhi-Guang,Li, Jin-Shan,Knochel, Paul
supporting information; experimental part, p. 9513 - 9516 (2011/02/24)
Updated classic: Primary and secondary alkylzinc reagents add to various aryldiazonium salts leading regioselectively to polyfunctional indoles by means of a [3,3]-sigmatropic shift and subsequent aromatization. This organometallic variation of the Fischer indole synthesis tolerates a wide range of functional groups and displays absolute regioselectivity. Copyright