55749-98-9 Usage
General Description
BOMBESIN (8-14) is a peptide fragment of bombesin, a neuropeptide that acts as a neurotransmitter in the brain and as a hormone in the gastrointestinal tract. It is derived from the precursor peptide progastrin-releasing peptide (GRP) and is known to bind to the bombesin receptor, a G protein-coupled receptor that is involved in regulating various physiological processes. BOMBESIN (8-14) has been studied for its potential role in cancer imaging and therapy, as it has been shown to bind to certain types of cancer cells that overexpress bombesin receptors, making it a potential targeting agent for diagnostic or therapeutic purposes. Additionally, BOMBESIN (8-14) has been investigated for its effects on food intake and body weight regulation, as it is believed to play a role in the regulation of appetite and energy balance.
Check Digit Verification of cas no
The CAS Registry Mumber 55749-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,4 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 55749-98:
(7*5)+(6*5)+(5*7)+(4*4)+(3*9)+(2*9)+(1*8)=169
169 % 10 = 9
So 55749-98-9 is a valid CAS Registry Number.
55749-98-9Relevant articles and documents
SYNTHESIS OF C-TERMINAL FRAGMENTS OF BOMBESIN AND THEIR ANALOGUES
Kuranova, I. L.,Churkina, S. I.,Dyudmirova, V. L.,Filonova, E. B.,Ibatullin, F. M.,et al.
, p. 475 - 484 (2007/10/02)
With the aim of structural-functional studies in the bombesin series, a number of bombesin fragments and analogues have been synthesized.The synthesis was performed by the carbodiimide method and by the activated-ester method.Fragments with the sequences