5579-63-5

Basic information

• Product Name: (E)-5,9-Dimethyl-4,8-decadienoic acid
• Synonyms: (E)-5,9-Dimethyl-4,8-decadienoic acid;Geranylacetic acid
• CAS NO: 5579-63-5
• Molecular Formula: C₁₂H₂₀O₂
• Molecular Weight: 196.29
• Mol File: 5579-63-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: -1.5 °C
• Boiling Point: 179 °C(Press: 19 Torr)
• Appearance: /
• Density: 0.938 g/cm3(Temp: 21 °C)
• PKA: 4.61±0.10(Predicted)
• CAS DataBase Reference: (E)-5,9-Dimethyl-4,8-decadienoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5,9-Dimethyl-4,8-decadienoic acid(5579-63-5)
• EPA Substance Registry System: (E)-5,9-Dimethyl-4,8-decadienoic acid(5579-63-5)

Safety Data

• Hazardous Substances Data: 5579-63-5(Hazardous Substances Data)

Usage

General Description

(E)-5,9-Dimethyl-4,8-decadienoic acid is a organic compound with the molecular formula C12H20O2. It is a unsaturated fatty acid with a branched structure, containing a double bond at the 5th and 9th carbon positions. (E)-5,9-Dimethyl-4,8-decadienoic acid is commonly found in natural sources such as plants and flowers, and is used in the production of perfumes and flavorings due to its strong and pleasant aroma. It also has antimicrobial properties and is being studied for potential applications in the pharmaceutical and cosmetic industries. Additionally, (E)-5,9-Dimethyl-4,8-decadienoic acid may have potential health benefits, including anti-inflammatory and antioxidant effects, making it a subject of interest in medical research.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 35520-09-3 9-methyl-5-oxo-dec-8-enoic acid 
• 72444-93-0 (4E,8E)-methyl 2-methoxycarbonyl-5,9-dimethyldeca-4,8-dienoate 
• 3796-70-1 trans geranyl acetone 
• 65017-88-1 2-cyclopropyl-6-methyl-hept-5-en-2-ol 
• 2270-59-9 1-bromo-4-methylpent-3-ene 
• 56946-66-8 2-(3-methylbut-2-en-1-yl)cyclohexane-1,3-dione 
• 6138-90-5 trans-geranyl bromide 
• 106-24-1 Geraniol 
• 62088-06-6 2-(3,7-diemthylocta-2E,6-dienyl)malonic acid 
• 19894-79-2 diethyl [(2E)-3,7-dimethylocta-2,6-dienyl]malonate 
• 19894-83-8 ethyl (E)-5,9-dimethyl-4,8-decadienoate 
• 105-53-3 diethyl malonate 
• 69405-35-2 homogeranyl bromide 

Downstream Products

• 32205-44-0 <(E)-5,9-Dimethyl-4,8-decadienyl>triphenylphosphonium iodide 
• 90879-27-9 (E)-5,9-Dimethyl-deca-4,8-dienoic acid (4-isopropyl-phenyl)-amide 
• 52567-91-6 (1S*,6R*)-1,7,7-Trimethyl-2-oxabicyclo<4.4.0>decan-3-one 
• 78038-67-2 trans-5,5,9-trimethyl-1-oxabicyclo<4.4.0>decan-2-one 
• 220453-88-3 (R)-3-((E)-(R)-2-Allyl-5,9-dimethyl-deca-4,8-dienoyl)-4-benzyl-oxazolidin-2-one 
• 19894-82-7 (4E,8E)-methyl 5,9-dimethyldeca-4,8-dienoate 
• 220453-87-2 (R)-4-Benzyl-3-((E)-5,9-dimethyl-deca-4,8-dienoyl)-oxazolidin-2-one 
• 90879-28-0 (E)-5,9-Dimethyl-deca-4,8-dienoic acid (4-ethyl-phenyl)-amide 
• 83732-41-6 (E)-(6,10-dimethyl-5,9-undecadien-2-ylidene)triphenylphosphorane 
• 90879-44-0 (E)-7-(3,3-Dimethyl-oxiranyl)-5-methyl-hept-4-enoic acid (4-isopropyl-phenyl)-amide 
• 90879-45-1 (E)-7-(3,3-Dimethyl-oxiranyl)-5-methyl-hept-4-enoic acid (4-ethyl-phenyl)-amide 
• 90879-46-2 ((E)-5,9-Dimethyl-deca-4,8-dienyl)-(4-isopropyl-phenyl)-amine 
• 90879-47-3 ((E)-5,9-Dimethyl-deca-4,8-dienyl)-(4-ethyl-phenyl)-amine 

Relevant articles and documents

2-(Acyloxy)ethylphosphonate analogues of prenyl pyrophosphates: synthesis and biological characterization

2-(Acyloxy)ethylphosphonate analogues of geranyl, farnesyl, and geranylgeranyl pyrophosphate have been prepared. Horner-Wadsworth-Emmons condensation of different terpene aldehydes with an unsymmetrical bisphosphonate was the key step in syntheses of the phosphonates bearing α,β-unsaturated acyloxy groups. After preparation of the respective phosphonic acids through reaction with TMSBr, both acids and esters were tested for their effects on DNA synthesis in human-derived myeloid and lymphoid leukemia cell lines. The phosphonate esters varied substantially in their ability to impair proliferation of the different cell lines, but testing against one possible target, farnesyl protein transferase (FPTase), revealed little impact at concentrations ranging up to 10μM. Because the corresponding 2,3-dihydro compounds showed similar biological activity, conjugate addition would not appear to be involved in the toxicity. Copyright (C) 2000 Elsevier Science Ltd.

Synthesis of phosphatidylinositol 3-kinase (PI3K) inhibitory analogues of the sponge meroterpenoid liphagal

Analogues of the sponge meroterpenoid liphagal (1) have been synthesized and evaluated for inhibition of PI3Kα and PI3Kα as part of a program aimed at developing new isoform-selective PI3K inhibitors. One of the analogues, compound 24, with IC50/sub

Asymmetric synthesis of rhopaloic acid a analogues and their biological properties

Some of rhopaloic acid A analogues were synthesized and their bioactivity was investigated on the basis of the inhibition of gastrulation of sea urchin embryos.