56074-20-5

Basic information

• Product Name: BOC-IMINODIACETIC ACID
• Synonyms: BOC-IDA;BOC-IDA-OH;BOC-IMINODIACETIC ACID;RARECHEM EM WB 0140;N-BOC-IMINODIACETIC ACID;2,2'-((tert-Butoxycarbonyl)azanediyl)diacetic acid;N-(tert-Butoxycarbonyl)iminodiacetic Acid;N-Boc-iminodiacetic acid >=96.0% (HPLC)
• CAS NO: 56074-20-5
• Molecular Formula: C₉H₁₅NO₆
• Molecular Weight: 233.22
• Product Categories: Glycine Derivatives;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 56074-20-5.mol
• Article Data: 26

Chemical Properties

• Melting Point: 117-120 °C
• Boiling Point: 412oC at 760 mmHg
• Flash Point: 203oC
• Appearance: White/Powder
• Density: 1.316g/cm3
• Vapor Pressure: 6.08E-08mmHg at 25°C
• Refractive Index: 1.502
• Storage Temp.: 2-8°C
• Solubility: Methanol
• PKA: 3.45±0.10(Predicted)
• BRN: 4435233
• CAS DataBase Reference: BOC-IMINODIACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-IMINODIACETIC ACID(56074-20-5)
• EPA Substance Registry System: BOC-IMINODIACETIC ACID(56074-20-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 56074-20-5(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline

Uses

Different sources of media describe the Uses of 56074-20-5 differently. You can refer to the following data:
1. Building block for preparing chemical libraries
2. Boc-Iminodiacetic Acid can be used as a novel α4β7 integrin peptide antagonists.

InChI:InChI=1/C9H15NO6/c1-9(2,3)16-8(15)10(4-6(11)12)5-7(13)14/h4-5H2,1-3H3,(H,11,12)(H,13,14)

Upstream product

• 142-73-4 iminodiacetic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 186393-22-6 rac-tert-butyl (3R,4S)-3,4-dihydroxypyrrolidine-1-carboxylate 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 

Downstream Products

• 206867-09-6 N-((tert-butyloxy)carbonyl)-N'-(5-((benzyloxycarbonyl)amino)-5-(methoxycarbonyl)pentyl)iminodiacetic acid monoamide 
• 188625-17-4 N-((tert-butyloxy)carbonyl)-N'-(2-(4-fluorophenyl)ethyl)iminodiacetic acid monoamide 
• 194996-01-5 N-((tert-butyloxy)carbonyl)-N'-(2-(4-hydroxyphenyl)ethyl)iminodiacetic acid monoamide 
• 155788-77-5 ({[Benzyl-(2-{benzyl-[2-(tert-butoxycarbonyl-carboxymethyl-amino)-acetyl]-amino}-ethyl)-carbamoyl]-methyl}-tert-butoxycarbonyl-amino)-acetic acid 
• 175353-91-0 N-((tert-butyloxy)carbonyl)-N'-(benzyl)iminodiacetic acid monoamide 
• 175354-29-7 N-((tert-butyloxy)carbonyl)-N'-cyclohexyliminodiacetic acid monoamide 
• 194996-43-5 {[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(4-hydroxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 194996-45-7 {[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 194996-44-6 {[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(3-methoxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 194996-42-4 {[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(4-methoxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 194996-12-8 {[3-(2-Oxo-pyrrolidin-1-yl)-propylcarbamoyl]-methyl}-(phenethylcarbamoyl-methyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Trifunctional reagents for substrate-protein conjugation: Application to pyrrolizidine alkaloid analogues

We report the syntheses of two pyrrolizidine alkaloid (PA) analogues (1 and 2) which exploit the novel substrate-protein coupling reagents 4 and 5. Analogues 1 and 2 incorporate the targeted PA substructural unit (i.e., a macrocyclic diester of retronecine), possess a handle for protein conjugation, and potentially maintain the conformational integrity of macrocyclic PAs.

Design, synthesis and evaluation of novel bifunctional tetrahydroxamate chelators for PET imaging of89Zr-labeled antibodies

Two compact and symmetrical bifunctional tetrahydroxamate chelators, 1 and 2, were synthesized and evaluated for labeling antibodies with89Zr for imaging with positron emission tomography. Using 2,2′-iminodiacetamide as the backbone, four hydro

Selective Extraction and Complexation Studies for Thorium(IV) with Bis-triamide Extractants: Synthesis, Solvent Extraction, EXAFS, and DFT

Three octyl-extended bis-triamide extractants (L1-L3) were designed and synthesized for the selective solvent extraction of Th(IV) over U(VI) in a kerosene-HNO3system. L1 and L2 exhibited good extraction property and selectivity toward Th(IV) o

Substance related with tophatib and preparation method and application thereof

The invention discloses a substance related with tophatib and a preparation method and application thereof. The substance is named as N,N'-diacetyl{(3R,4R)-4-methyl-3-[methyl(7H-pyrrole[2,3-D]pyrimidine-4-yl)amine]piperidine-1-yl}imine. The impurity is characterized in that the generation level is lower in the condensation reaction process; however, the impurity has the uniform main functional groups with the tophatib, the cleaning effect is limited in the subsequent salting and refining process, and the influence to the qualities of crude drug and finished product of tophatib is larger; by detecting the existence of the impurity, the qualities of the raw material and preparation of the tophatib can be effectively determined.