56252-83-6

Basic information

• Product Name: 1-Methyl-4-stearoylpiperazine
• Synonyms: 1-Methyl-4-stearoylpiperazine
• CAS NO: 56252-83-6
• Molecular Formula: C23H46 N2 O
• Molecular Weight: 366.62
• Mol File: 56252-83-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-4-stearoylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-4-stearoylpiperazine(56252-83-6)
• EPA Substance Registry System: 1-Methyl-4-stearoylpiperazine(56252-83-6)

Safety Data

• Hazardous Substances Data: 56252-83-6(Hazardous Substances Data)

Usage

Chemical structure

1-Methyl-4-stearoylpiperazine consists of a piperazine ring with a stearoyl group (a long-chain fatty acid) and a methyl group attached to it.

Derivative

It is a derivative of piperazine (a six-membered heterocyclic organic compound with two nitrogen atoms) and stearic acid (a saturated fatty acid).

Application in pharmaceutical industry

This compound is commonly used as a building block for the synthesis of various drugs and active pharmaceutical ingredients.

Pharmacological properties

1-Methyl-4-stearoylpiperazine exhibits potential pharmacological properties such as antiviral, antibacterial, and anticancer activities.

Drug development

Due to its pharmacological properties, it is an important target for drug development.

Chemical research

The compound is also used in chemical research for various purposes.

Industrial applications

1-Methyl-4-stearoylpiperazine is used as a surfactant and emulsifier in different industries.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 112-76-5 Stearoyl chloride 

Downstream Products

• 32705-98-9 1,1-dimethyl-4-stearoylpiperazin-1-ium iodide 

Relevant articles and documents

Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part i

We synthesized novel aliphatic amido-quaternary ammonium salts in an effort to discover anticancer agents that increase Ras homolog gene family, member B, (RhoB) levels. These compounds exert anti-proliferative activities against several human cancer cell types. Seventeen compounds, varying in aliphatic carbon chain length and N-substituents, were synthesized and their biological activities were evaluated. Of these 17 compounds, compound 3i emerged as the most promising anticancer compound by promoting apoptosis through the RhoB mediated pathway. Potent biological activities observed for these novel aliphatic amido-quaternary ammonium salt analogues support their potential as anticancer, chemotherapeutic agents.

Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes

This invention provides compositions for enhancing penetration of physiologically active agents through the skin or mucosal membranes and for retaining these agents in body tissues, said composition comprising effective amounts of a physiologically-active agent and a compound represented by the general formula STR1 wherein X may represent sulfur, oxygen or nitrogen; a and b may be 0 or 1, c may be 0, 1 or 2, except that when X is oxygen, a, b and c are 0, when X is nitrogen c is 0 and only one of a or b is 1, and when X is sulfur a and b are 0; A is a branched or a straight chain, divalent aliphatic radical having from 0 to 2 double bonds; R' is selected from the group consisting of H, a lower alkyl group having from 1 to 4 carbon atoms, phenyl, lower alkyl or halogen substituted phenyl, acetamido, halogen, piperidinyl, lower alkyl or halogen substituted piperidinyl, carbalkoxy, carboxamide, and alkanoyl; and R is hydrogen or a lower alkyl group having from 1 to 4 carbon atoms, STR2 wherein R" is H or halogen, and salts, e.g. acid or quaternary derivatives, thereof. These compositions are useful in topical or transdermal applications of the physiologically-active agent.