56440-28-9 Usage
Description
3-Aminopyrrolidin-2-one, with the CAS number 2483-65, is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique molecular structure, which allows it to be a versatile building block in the development of different drugs.
Uses
Used in Pharmaceutical Industry:
3-Aminopyrrolidin-2-one is used as a key intermediate for the preparation of conformationally restricted inhibitors of angiotensin-converting enzyme (ACE). These inhibitors play a crucial role in the treatment of hypertension and other cardiovascular diseases by regulating the activity of the renin-angiotensin system.
3-Aminopyrrolidin-2-one is also used as a building block in the preparation of 2-aminoquinolines, which act as melanin concentrating hormone receptor (MCH-1R) antagonists. These antagonists have potential applications in the treatment of obesity, depression, and other disorders related to the regulation of energy balance and mood.
Furthermore, 3-Aminopyrrolidin-2-one is utilized in the synthesis of cycloalkyl, lactam, lactone, and related compounds. These compounds are designed to inhibit the release and/or synthesis of β-amyloid peptide, which is associated with the development of Alzheimer's disease. By targeting this peptide, these compounds may help in the development of therapeutic strategies to combat neurodegenerative disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 56440-28-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,4 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 56440-28:
(7*5)+(6*6)+(5*4)+(4*4)+(3*0)+(2*2)+(1*8)=119
119 % 10 = 9
So 56440-28-9 is a valid CAS Registry Number.