56452-73-4

Basic information

• Product Name: (S)-5-(1-Hydroxy-ethyl)-dihydro-furan-2-one
• CAS NO: 56452-73-4
• Molecular Weight: 130.144
• Mol File: 56452-73-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-5-(1-Hydroxy-ethyl)-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(1-Hydroxy-ethyl)-dihydro-furan-2-one(56452-73-4)
• EPA Substance Registry System: (S)-5-(1-Hydroxy-ethyl)-dihydro-furan-2-one(56452-73-4)

Safety Data

• Hazardous Substances Data: 56452-73-4(Hazardous Substances Data)

Upstream product

• 41143-12-8 hex-4-ynoic acid 
• 6089-09-4 4-pentynoic acid 
• 124558-70-9 (S)-4-Ethylsulfanyl-5-((S)-1-hydroxy-ethyl)-5H-furan-2-one 
• 1577-20-4 (E)-hex-4-enoic acid 

Downstream Products

• 1422255-62-6 (4R,5R)-benzyl 4-azido-5-fluorohexanoate 
• 1422255-60-4 (4S,5R)-benzyl 5-fluoro-4-hydroxyhexanoate 
• 1422255-66-0 (4S,5S)-5-fluoro-4-((S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanamido)hexanoic acid 
• 1422255-67-1 (4R,5R)-5-fluoro-4-((S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanamido)hexanoic acid 
• 749821-78-1 1-dimethylamino-4,5-dihydroxy-L-threo-hexane 
• 35903-48-1 2,3,6-tri-deoxy-L-threo-hexose 
• 89158-15-6 p-nitrobenzoate of L-(+)-rhodinono-γ-lactone 
• 89158-14-5 p-nitrobenzoate of D-(+)-amicetono-γ-lactone 

Relevant articles and documents

(+/-)-erythro-γ,δ-Dihydroxycarboxylic Acid Lactones from a β-Lithiopropionate Equivalent and α-Chloroaldehydes

Reaction of β-ethylthio-β-lithioacrylate 1A with α-chloroaldehydes furnished predominantly the erythro products 3, which were isolated as γ-lactones 4.At room temperature intermediates 3 are transformed into the (+/-)-erythro-γ,δ-dihydroxycarboxylic acid γ-lactones 8.Raney nickel treatment provided interesting natural γ-lactone derivatives; thus, from erythro-8c the socalled L-factor erythro-9c was obtained.Similarly, from β-methoxy β-lithioacrylate 10A the (+/-)-erythro-γ,δ-dihydroxycarboxylic acid δ-lactone erythro-11 was gained.