56456-19-0

Basic information

• Product Name: 2-BENZYLOXYETHYL CHLOROFORMATE
• Synonyms: 2-BENZYLOXYETHYL CHLOROFORMATE;Carbonochloridic acid, 2-(phenylMethoxy)ethyl ester;2-Benzyloxyethyl chloroformate 97%
• CAS NO: 56456-19-0
• Molecular Formula: C₁₀H₁₁ClO₃
• Molecular Weight: 214.65
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 56456-19-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 282.7°C at 760 mmHg
• Flash Point: 230 °F
• Appearance: /
• Density: 1.19 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.36 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.508(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BENZYLOXYETHYL CHLOROFORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLOXYETHYL CHLOROFORMATE(56456-19-0)
• EPA Substance Registry System: 2-BENZYLOXYETHYL CHLOROFORMATE(56456-19-0)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 56456-19-0(Hazardous Substances Data)

Usage

General Description

2-Benzyloxyethyl chloroformate is also referred to as 2-phenylmethoxyethyl carbonochloridate (IUPAC name).

InChI:InChI=1/C10H11ClO3/c11-10(12)14-7-6-13-8-9-4-2-1-3-5-9/h1-5H,6-8H2

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 622-08-2 2-Benzyloxyethanol 
• 75-44-5 phosgene 

Downstream Products

• 162538-01-4 Dimethyl-carbamic acid 2-benzyloxy-ethyl ester 
• 869189-75-3 1-[2-(benzyloxy)ethyl] 4-methyl 4-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]methylpiperidine-1,4-dicarboxylate 
• 62124-67-8 1-(2-benzyloxyethoxycarbonyl)-2-(4-thiazolyl)-benzimidazole 
• 1228443-13-7 C₄₈H₃₆N₂O₁₀ 
• 56456-26-9 3-Acetylamino-5-[(2-benzyloxy-ethoxycarbonylamino)-methyl]-2,4,6-triiodo-benzoic acid 
• 56456-25-8 3-Amino-5-[(2-benzyloxy-ethoxycarbonylamino)-methyl]-2,4,6-triiodo-benzoic acid 

Relevant articles and documents

5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, an optionally substituted lower alkenyl group, a cycloalkyl group or a lower acyl group etc.; Q is a hydrogen atom or an optionally substituted lower alkyl group; and Z is a hydrogen atom or a hydroxy group etc., or a pharmaceutically acceptable salt thereof, which exert a potent and selective activated blood coagulation factor X inhibitory activity and is useful as an agent for the prevention or treatment of a disease occurred associating an activated blood coagulation factor X, a pharmaceutical composition comprising the same and an intermediate thereof. These compounds are useful as preventives or remedies for various diseases such as brain infarction, cerebral thrombosis, cerebral embolism, TIA, cerebral vascular jerk, Alzheimer's diseases, myocardial infarction, heart attack, heart failure, thrombosis, pulmonary infarction and pulmonary embolism.

Antifungal 1-substituted benzimidazoles

New benzimidazoles substituted at the 1-position with carbonyl substituents and at the 2-position with a 4-thiazolyl group are effective fungicides and anthelmintics exhibiting particularly useful hydrophilic and lypophilic effects. The compounds as well as processes for their preparation are described along with antifungal and anthelmintic compositions for their use. The 1-position substituent is a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy carbonyl group of a chain with up to 4 ethoxy groups connected to the carbonyl. The compounds are generally prepared by contacting a 1-unsubstituted benzimidazole with a loweralkoxy or phenylloweralkoxy substituted ethoxy or polyethoxy chloroformate.