5673-38-1

Basic information

• Product Name: N-(isopropylcarbamoyl)-4-methylbenzenesulfonamide
• Synonyms: N-(isopropylcarbamoyl)-4-methylbenzenesulfonamide
• CAS NO: 5673-38-1
• Molecular Weight: 256.326
• Mol File: 5673-38-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(isopropylcarbamoyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(isopropylcarbamoyl)-4-methylbenzenesulfonamide(5673-38-1)
• EPA Substance Registry System: N-(isopropylcarbamoyl)-4-methylbenzenesulfonamide(5673-38-1)

Safety Data

• Hazardous Substances Data: 5673-38-1(Hazardous Substances Data)

Upstream product

• 17614-10-7 phenyl N-isopropylcarbamate 
• 70-55-3 toluene-4-sulfonamide 
• 1795-48-8 Isopropyl isocyanate 
• 1424-52-8 p-tolylsulfonyl isothiocyanate 
• 4083-64-1 Tosyl isocyanate 
• 18522-92-4 sodium p-toluenesulfonamide 
• 4128-37-4 1,3-diisopropylurea 
• 19978-10-0 Isopropyl(tosyl)carbodiimid 
• 91430-62-5 N-tosyl-N'-isopropylthiourea 

Relevant articles and documents

A facile synthesis of sulfonylureas: Via water assisted preparation of carbamates

A novel and simple approach to the synthesis of sulfonylureas has been reported. It involved the reaction of various amines with diphenyl carbonate to yield the corresponding carbamates, which subsequently reacted with different sulphonamides to produce different sulfonylureas in excellent yields. The first reaction of diphenyl carbonate with amines was carried out in aqueous:organic (H2O:THF, 90:10) medium at room temperature to produce carbamates that paved a straightforward route to sulfonylureas after reaction with sulfonamides. The above process avoided traditional multistep protocols and the use of hazardous, irritant, toxic and moisture sensitive reagents such as phosgene, isocyanates and/or chloroformates.

KINETICS AND THERMODYNAMICS OF THE SYNTHESIS OF N-ALKYL-N'-TOLUENE-p-SULFONYLUREA

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