5690-46-0

Basic information

• Product Name: 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE
• Synonyms: AKOS BBS-00007375;2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE;2-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE
• CAS NO: 5690-46-0
• Molecular Formula: C₁₂H₈N₂O₂
• Molecular Weight: 212.2
• Mol File: 5690-46-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 265 °C
• Boiling Point: 463°Cat760mmHg
• Flash Point: 233.8°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 9.44E-09mmHg at 25°C
• Refractive Index: 1.754
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE(5690-46-0)
• EPA Substance Registry System: 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE(5690-46-0)

Safety Data

• Hazardous Substances Data: 5690-46-0(Hazardous Substances Data)

Usage

Uses

2-Amino-benzo[de]isoquinoline-1,3-dione is an antiviral compound that exhibits antiherpetic activity against herpes simplex viruses HSV-1 and HSV-2.

InChI:InChI=1/C12H8N2O2/c13-14-11(15)8-5-1-3-7-4-2-6-9(10(7)8)12(14)16/h1-6H,13H2

Upstream product

• 19162-45-9 N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)benzamide 
• 109395-64-4 2-((3-nitrobenzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 5810-79-7 2-(phenylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 1006570-57-5 2-(2,4-dichloro-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 387363-94-2 2-((4-hydroxy-3-methoxybenzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 1630974-95-6 2-(3-methoxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 349485-64-9 2-(2-methoxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 349485-92-3 2-(4-hydroxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 94374-88-6 2-benzylideneamino-benzo[de]isoquinolin-1,3-dione 
• 19162-44-8 N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butyramide 
• 19162-43-7 N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propanamide 
• 19162-41-5 N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetamide 

Downstream Products

• 102241-44-1 2-(3-phenyl-propylidenamino)-benz[de]isoquinoline-1,3-dione 
• 57388-02-0 10-phenyl-benzo[de][1,2,4]triazolo[5,1-a]isoquinolin-7-one 
• 109395-64-4 2-(3-nitro-benzylidenamino)-benz[de]isoquinoline-1,3-dione 
• 109394-13-0 2-(4-nitro-benzylidenamino)-benz[de]isoquinoline-1,3-dione 
• 111384-88-4 2-(4-nitro-benzoylamino)-benz[de]isoquinoline-1,3-dione 
• 108367-43-7 2-(3-chloro-benzylidenamino)-benz[de]isoquinoline-1,3-dione 
• 102469-92-1 (E)-2-((4-(dimethylamino)benzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 109394-12-9 2-(2-nitro-benzylidenamino)-benz[de]isoquinoline-1,3-dione 
• 81-83-4 1,8-Naphthalimide 
• 349485-64-9 2-(2-methoxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 1630974-95-6 2-(3-methoxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 109395-64-4 2-((3-nitrobenzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 349485-92-3 2-(4-hydroxy-benzylidene)amino-benzo[de]isoquinolin-1,3-dione 
• 387363-94-2 2-((4-hydroxy-3-methoxybenzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 

Relevant articles and documents

N-Amino-1,8-Naphthalimide is a Regenerated Protecting Group for Selective Synthesis of Mono-N-Substituted Hydrazines and Hydrazides

A new route to synthesis of various mono-N-substituted hydrazines and hydrazides by involving in a new C?N bond formation by using N-amino-1,8-naphthalimide as a regenerated precursor was invented. Aniline and phenylhydrazines are reproduced upon reacting these individually with 1,8-naphthalic anhydride followed by hydrazinolysis. The practicality and simplicity of this C?N dihalo alkanes; developed a synthon for bond formation protocol was exemplified to various hydrazines and hydrazides. N-amino-1,8-naphthalimide is suitable synthon for transformation for selective formation of mono-substituted hydrazine and hydrazide derivatives. Those are selective mono-amidation of hydrazine with acid halides; mono-N-substituted hydrazones from aldehydes; synthesis of N-aminoazacycloalkanes from acetohydrazide scaffold and inserted to hydroxy derivatives; distinct synthesis of N,N-dibenzylhydrazines and N-benzylhydrazines from benzyl halides; synthesis of N-amino-amino acids from α-halo esters. Ecofriendly reagent N-amino-1,8-naphthalimide was regenerated with good yields by the hydrazinolysis in all procedures.