5700-75-4

Basic information

• Product Name: 2-{[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxamide
• Synonyms: 3-thiophenecarboxamide, 2-[[(2E)-3-[4-(1,1-dimethylethyl)phenyl]-1-oxo-2-propen-1-yl]amino]-4,5-dimethyl-
• CAS NO: 5700-75-4
• Molecular Formula: C₈H₁₃NO₆
• Molecular Weight: 356.4818
• Mol File: 5700-75-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 510.3°C at 760 mmHg
• Flash Point: 262.4°C
• Density: 1.193g/cm³
• Vapor Pressure: 1.57E-10mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: 2-{[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxamide(5700-75-4)
• EPA Substance Registry System: 2-{[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino}-4,5-dimethylthiophene-3-carboxamide(5700-75-4)

Safety Data

• Hazardous Substances Data: 5700-75-4(Hazardous Substances Data)

Usage

Molecular structure

The compound contains a thiophene ring and an amide functional group, with a long carbon chain connecting the two.

Appearance

Yellow crystalline substance

Use

Research and pharmaceutical applications, potential pharmacological properties

Handling precautions

Handle with caution and use appropriate safety measures due to not fully understood properties and potential hazards.

Upstream product

• 56-86-0 L-glutamic acid 
• 501-52-0 3-Phenylpropionic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 151418-18-7 Aethoxykohlensaeure-dihydrozimtsaeure-anhydrid 

Relevant articles and documents

Ecological base-conditioned preparation of dipeptides using unprotected α-amino acids containing hydrophilic side chains

The coupling reactions of 3-phenylpropanoic acid and Ncarboxybenzyl á-amino acids with unprotected á-amino acids containing hydrophilic side chains such as aliphatic alcohol, aromatic alcohol, thiol, carboxylic acid, and amide afforded the corresponding amides in 6696% yield without racemization via the corresponding mixed carbonic carboxylic anhydrides under basic conditions through an ecological green synthetic method.

Convenient peptide synthesis using unprotected α-amino acids containing another hydrophilic moiety under basic conditions

Carboxylic acids 1 and 7 reacted effectively with unprotected α-amino acids 2 containing another hydrophilic moiety under basic conditions via activation by ethyl chloroformate and triethylamine to afford the corresponding amides in 7499% yields.