570411-28-8

Basic information

• Product Name: 2-Propenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)-, (2E)-
• CAS NO: 570411-28-8
• Molecular Formula: C20H20N2O3
• Molecular Weight: 336.39
• Mol File: 570411-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)-, (2E)-(570411-28-8)
• EPA Substance Registry System: 2-Propenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)-, (2E)-(570411-28-8)

Safety Data

• Hazardous Substances Data: 570411-28-8(Hazardous Substances Data)

Upstream product

• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 971-74-4 serotonin creatinine sulfate 

Downstream Products

• 570411-29-9 ethyl 2-[5-[3-[2-[2-(4-methoxyphenyl)ethenyl]carbonylamino]ethyl]indolyloxy]-3-(3,4-dimethoxyphenyl)-3-oxo-propanoate 

Relevant articles and documents

Ipobscurines C and D: Macrolactam-type indole alkaloids from the seeds of Ipomoea obscura

Separation of the methanolic seed extract of Ipomoea obscura afforded five indole alkaloids, three of them (ipobscurines B-D) being new natural products of a unique structural type characterized as serotonin hydroxycinnamic acid amide-type conjugates with a second phenylpropanoid moiety forming an ether with the 5-OH position of the indole nucleus. Due to an oxidative phenolic coupling between the two phenylpropanoid moieties of the supposed precursor ipobscurine B two 21-membered macrolactams with a phenol ether partial structure are formed: the trans-cis isomers ipobscurines C and D. Their structures were established on the basis of spectral data. Moreover, total synthesis of the racemic erythro- and threo-ipobscurine B 4′,4″-dimethyl ethers and the comparison with the corresponding derivative of natural (-)-ipobscurine B proved an erythro configuration of the latter.