57045-82-6

Basic information

• Product Name: CHLOROFORMIC ACID N-NONYL ESTER
• Synonyms: CHLOROFORMIC ACID N-NONYL ESTER;CHLOROFORMIC ACID NONYL ESTER;NONYL CHLOROFORMATE;Nonyl chloridocarbonate
• CAS NO: 57045-82-6
• Molecular Formula: C₁₀H₁₉ClO₂
• Molecular Weight: 206.71
• Mol File: 57045-82-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 248.2°C at 760 mmHg
• Flash Point: 79.6°C
• Appearance: /
• Density: 0.97
• Vapor Pressure: 0.0245mmHg at 25°C
• Refractive Index: 1.4330-1.4360
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: CHLOROFORMIC ACID N-NONYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CHLOROFORMIC ACID N-NONYL ESTER(57045-82-6)
• EPA Substance Registry System: CHLOROFORMIC ACID N-NONYL ESTER(57045-82-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: 2742
• HazardClass: 6.1/8
• PackingGroup: II
• Hazardous Substances Data: 57045-82-6(Hazardous Substances Data)

Usage

General Description

Chloroformic acid N-nonyl ester, also known as nonyl chloroformate, is a chemical compound with the formula C9H17ClO2. It is an organic compound commonly used as a reagent for organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. Nonyl chloroformate is a colorless liquid with a sharp, irritating odor, and is highly reactive due to the presence of a reactive chloroformate group. It is used in the production of dyes, perfumes, and in the synthesis of various organic compounds. Nonyl chloroformate is also a potential skin and eye irritant and should be handled with care in a laboratory or industrial setting.

InChI:InChI=1/C10H19ClO2/c1-2-3-4-5-6-7-8-9-13-10(11)12/h2-9H2,1H3

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 143-08-8 nonyl alcohol 
• 75-44-5 phosgene 

Downstream Products

• 1380431-41-3 nonyl 4,5-dimethoxy-2-nitrobenzylcarbamate 
• 121679-83-2 Carbonic acid nonyl ester 4-[5-(4-nonyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-phenyl ester 

Relevant articles and documents

Anti-HIV-Active Nucleoside Triphosphate Prodrugs

We disclose a study on nucleoside triphosphate (NTP) analogues in which the γ-phosphate is covalently modified by two different biodegradable masking units and d4T as nucleoside analogue that enable the delivery of d4TTP with high selectivity in phosphate buffer (pH 7.3) and by enzyme-triggered reactions in human CD4+ T-lymphocyte CEM cell extracts. This allows the bypass of all steps normally needed in the intracellular phosphorylation. These TriPPPro-nucleotides comprising an acyloxybenzyl (AB; ester) or an alkoxycarbonyloxybenzyl (ACB; carbonate) in combination with an ACB moiety are described as NTP delivery systems. The introduction of these two different groups led to the selective formation of γ-(ACB)-d4TTPs by chemical hydrolysis and in particular by cell extract enzymes. γ-(AB)-d4TTPs are faster cleaved than γ-(ACB)-d4TTPs. In antiviral assays, the compounds are highly active against HIV-1 and HIV-2 in wild-type CEM/O cells and more importantly in thymidine kinase-deficient CD4+ T-cells (CEM/TK-).

Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase

Compounds of formula (I) wherein the groups are as defined in the description are disclosed. The compounds of formula (I) are endowed with reversible inhibiting activity of carnitine palmitoyl-transferase and are useful in the preparation of medicaments useful in the pathologies related to a hyperactivity of carnitine palmitoyl-transferase, such as hyperglycemia, diabetes and pathologies related thereto, heart failure, ischemia.