57148-86-4

Basic information

• Product Name: 3-(2-HYDROXY-5-METHYLPHENYL)PYRAZOLE
• Synonyms: 4-METHYL-2-(1H-PYRAZOL-3-YL)PHENOL;3-(2-HYDROXY-5-METHYLPHENYL)PYRAZOLE;1H-5-(2'-HYDROXY-5'-METHYLPHENYL)PYRAZOLE;5-(2`-hydroxy-5`-methyphenyl)pyrazole;5-(2Hydroxy-5methylphenyl) pyrazole
• CAS NO: 57148-86-4
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Product Categories: Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
• Mol File: 57148-86-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 105-107°C
• Boiling Point: 373.4 °C at 760 mmHg
• Flash Point: 179.6 °C
• Appearance: /
• Density: 1.235 g/cm³
• CAS DataBase Reference: 3-(2-HYDROXY-5-METHYLPHENYL)PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-HYDROXY-5-METHYLPHENYL)PYRAZOLE(57148-86-4)
• EPA Substance Registry System: 3-(2-HYDROXY-5-METHYLPHENYL)PYRAZOLE(57148-86-4)

Safety Data

• Hazardous Substances Data: 57148-86-4(Hazardous Substances Data)

Usage

General Description

3-(2-Hydroxy-5-methylphenyl)pyrazole is a chemical compound with a molecular formula C11H11N3O. It is a pyrazole derivative, and its structure consists of a pyrazole ring with a hydroxyl group and a methyl group attached to a benzene ring. 3-(2-Hydroxy-5-methylphenyl)pyrazole has been studied for its potential pharmaceutical applications, including its role as an inhibitor of certain enzymes and its potential as a therapeutic agent for various medical conditions. Its properties and potential uses make it a subject of interest in the field of medicinal chemistry and drug development.

Upstream product

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Relevant articles and documents

Catalysis and kinetics for alternating copolymerization of carbon dioxide with epoxides using dinuclear nickel catalysts of pyrazolyl based diamine-bisphenolate ligands

The synthesis of structurally well-characterized dinuclear nickel complexes bearing a new type of pyrazolyl based diamine-bisphenolate ligand was reported for the first time. Catalysis towards nickel-catalyzed copolymerization of CO2 with cyclohexene oxide (CHO) by these newly prepared bimetallic complexes was systematically investigated. Particularly, dinickel complex 4 supporting 2-nitrophenoxide coligands was demonstrated to effectively catalyze CO2-copolymerization of CHO, 4-vinyl-1,2-cyclohexene oxide or cyclopentene oxide, generating the corresponding CO2-based polycarbonates with >99% carbonate linkages under optimal conditions. Kinetic studies of CO2/CHO copolymerization revealed that such copolymerization catalysis is first-order in dinickel complex 4 and second-order in CHO concentration.