57268-16-3 Usage
General Description
5-Bromo-2-methylthiazole is a chemical compound with the molecular formula C5H5BrNS. It is a highly reactive heterocyclic compound, commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a reagent in organic synthesis, particularly in the creation of thiazole derivatives. 5-Bromo-2-methylthiazole is known for its strong odor and is considered hazardous when inhaled or ingested. It is important to handle this chemical with proper precautions to avoid any potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 57268-16-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,6 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57268-16:
(7*5)+(6*7)+(5*2)+(4*6)+(3*8)+(2*1)+(1*6)=143
143 % 10 = 3
So 57268-16-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H4BrNS/c1-3-6-2-4(5)7-3/h2H,1H3
57268-16-3Relevant articles and documents
COURSE OF BROMINATION OF THIAZOLE AND 2-METHYLTHIAZOLE
Gol'dfarb, Ya. L.,Gromova, G. P.,Belen'kii, L. I.
, p. 663 - 666 (2007/10/02)
Bromination of thiazole by bromine in the presence of aluminium chloride in neutral solvent or without solvent takes place at the 2-position.Such an orientation contradicts the traditional addition-cleavage mechanism, and agrees with the ylid mechanism of electrophilic substitution. 2-Methylthiazole brominates at the 5-position, and the reaction is impeded in the presence of aluminium chloride; this is due to heterocycle deactivation by complexation with the Lewis acid at the nitrogen atom.
