5736-03-8

Basic information

• Product Name: 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
• Synonyms: GLYCERALDEHYDE, CYCLIC ACETAL WITH ACETONE;2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBALDEHYDE;2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE;2,3-O-ISOPROPYLIDENEGLYCERALDEHYDE;1,3-DIOXOLANE-4-CARBOXALDEHYDE, 2,2-DIMETHYL-;ACETONE, CYCLIC FORMYLETHYLENE ACETAL;RACEMIC-SOLKETYL ALDEHYDE;4-Formyl-2,2-dimethyloxolane
• CAS NO: 5736-03-8
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.14
• EINECS: 227-244-2
• Mol File: 5736-03-8.mol
• Article Data: 29

Chemical Properties

• Melting Point: 105-110 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 180.82°C (rough estimate)
• Flash Point: 44.6 °C
• Appearance: /
• Density: 1.1066 (rough estimate)
• Vapor Pressure: 1.76mmHg at 25°C
• Refractive Index: 1.4189 (estimate)
• CAS DataBase Reference: 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(5736-03-8)
• EPA Substance Registry System: 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(5736-03-8)

Safety Data

• Hazardous Substances Data: 5736-03-8(Hazardous Substances Data)

Usage

General Description

2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chemical compound that is categorized in the group of heterocyclic and aldehyde compounds. It possesses methyl and carboxaldehyde functional groups incorporated into a dioxolane ring structure. 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is used in the field of synthetic organic chemistry, primarily as a chemical intermediate in the synthesis of other compounds. Specific information about its use, safety profiles, environmental and health impacts may not be readily available, demanding careful handling and further research into its properties and effects.

InChI:InChI=1/C6H10O3/c1-6(2)8-4-5(3-7)9-6/h3,5H,4H2,1-2H3

Upstream product

• 67-64-1 acetone 
• 56-82-6 Glyceraldehyde 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 53735-98-1 (1S,2S)-1,2-bis[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol 
• 126694-15-3 4,5-isopropylidene-D-arabinose dibenzyl thioacetal 
• 22323-78-0 (1R,2R)-1,2-bis((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 860649-42-9 5,6-0-isopropylidene ascorbic acid 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 77-76-9 2,2-dimethoxy-propane 
• 61821-85-0 (2,2-Dimethyl-[1,3]dioxolan-4-yl)-ethanol 
• 116-11-0 2-Methoxypropene 
• 82188-74-7 O¹,O²;O⁵,O⁶-diisopropylidene-mannitol 
• 312583-58-7 (1S,2S)-1,2-bis(2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 53735-98-1 1,2:5,6-di-O-isopropylidene-D-glucitol 

Downstream Products

• 110598-85-1 [(R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-allyloxy]-methyl-diphenyl-silane 
• 110598-85-1 [(R)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-allyloxy]-methyl-diphenyl-silane 
• 141887-87-8 2,2-Dimethyl-4-((E)-4-phenyl-but-1-enyl)-[1,3]dioxolane 
• 142696-31-9 (E)-2-Benzyloxycarbonylamino-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)-acrylic acid methyl ester 
• 142696-32-0 (Z)-2-Benzyloxycarbonylamino-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)-acrylic acid methyl ester 
• 86559-77-5 Benzoic acid cyano-(2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl ester 
• 103773-42-8 4,5-O-isopropylidene-2-pentenal 
• 105662-92-8 (Z)-N-(2,2-dimethyl-1,3-dioxolan-4-yl)methylenebenzylamine N-oxide 
• 84629-17-4 1-(2,2-Dimethyl-1,3-dioxolan-4-yl)-4-phenyl-1,4-butandion 
• 90493-96-2 2,2-dimethyl-1,3-dioxolane-4-carboxylic acid chloride 
• 143159-97-1 (+)-(3R,4S)-cis-1-benzyl-3-benzyloxy-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-azetidinone 
• 1263469-89-1 (3α,5R,6β,22Z,24R)-24-benzyloxy-6-methoxy-3,5-cyclocholest-22-ene 
• 1263469-88-0 (3α,5R,6β,22E,24R)-24-benzyloxy-6-methoxy-3,5-cyclocholest-22-ene 
• 1350461-60-7 (R)-1-(benzyloxycarbonyl)-5-[(R)-[4-methoxy-2-(methylthio)phenylamino][(R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl]-1H-pyrrol-2(5H)-one 

Relevant articles and documents

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Chirality plays a pivotal role in chemistry and biology, e.g., structure-specific targeting in drug development or the lock-and-key theory of enzyme interactions. Determining absolute configurations of chiral molecules is essential to understanding such mechanisms and to developing chemical processes involving chiral compounds. In particular, this becomes obvious in the understanding of chemical reaction networks in the context of the origins of life. A stereochemical reference compound that can be correlated with sugars, amino acids, etc. is of great interest. Here, we present the synthesis of enantiopure (R,R)-2,3-dideuterooxirane, of which the absolute configuration has been unambiguously determined by foil-induced Coulomb explosion imaging, and the correlation with the configuration of D-(+)-glyceraldehyde.