57403-74-4

Basic information

• Product Name: (R)-3-METHYLHEPTANOIC ACID
• Synonyms: (R)-3-METHYLHEPTANOIC ACID;(3R)-3-Methylheptanoic acid
• CAS NO: 57403-74-4
• Molecular Formula: C₈H₁₆O₂
• Molecular Weight: 144.21
• Mol File: 57403-74-4.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-METHYLHEPTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-METHYLHEPTANOIC ACID(57403-74-4)
• EPA Substance Registry System: (R)-3-METHYLHEPTANOIC ACID(57403-74-4)

Safety Data

• Hazardous Substances Data: 57403-74-4(Hazardous Substances Data)

Usage

General Description

(R)-3-Methylheptanoic acid is a chemical compound with the molecular formula C8H16O2. It is a carboxylic acid with a seven-carbon hydrocarbon chain and a methyl group attached to the third carbon. (R)-3-METHYLHEPTANOIC ACID is classified as an organic acid and is commonly used as a precursor or intermediate in the synthesis of various pharmaceuticals and other organic compounds. It may also be used as a flavoring agent in the food and beverage industry due to its characteristic odor and taste. Additionally, (R)-3-methylheptanoic acid has been studied for its potential biological and pharmacological properties, making it a subject of interest in the field of medicinal chemistry.

Upstream product

• 198956-42-2 (2S)-2-Benzylhexane 
• 84817-84-5 3-methylideneheptanoic acid 
• 109-65-9 1-bromo-butane 
• 199006-79-6 (R)-(+)-N-(1-ethyl-2-hydroxy)ethyl-N-(2-fluorobenzyl) crotonamide 
• 96864-26-5 (R)-3-Methyl-heptanoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 88020-53-5 (S)-3-Methyl-heptanoic acid ((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 77727-24-3 (E)-2-((S)-Benzenesulfinyl)-but-2-enoic acid methyl ester 
• 105526-90-7 (5S)-N-[(3R)-methylheptanoyl]-5-triphenylmethoxymethyl-2-pyrrolidinone 
• 3200-11-1 1-phenyl-2-methylhexane 

Downstream Products

• 1070-32-2 (R)-(+)-3-Methyl-1-heptanol 
• 27608-03-3 (+)-(R)-3-methylheptanal 

Relevant articles and documents

Neutral iridium catalysts with chiral phosphine-carboxy ligands for asymmetric hydrogenation of unsaturated carboxylic acids

We developed neutral iridium catalysts with chiral spiro phosphine-carboxy ligands (SpiroCAP) for asymmetric hydrogenation of unsaturated carboxylic acids. Different from the cationic Crabtree-type catalysts, the iridium catalysts with chiral spiro phosphine-carboxy ligands are neutral and do not require the use of a tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (BArF?) counterion, which is necessary for stabilizing cationic Crabtree-type catalysts. Another advantage of the neutral iridium catalysts is that they have high stability and have a long lifetime in air. The new iridium catalysts with chiral spiro phosphine-carboxy ligands exhibit unprecedented high enantioselectivity (up to 99.4% ee) in the asymmetric hydrogenations of various unsaturated carboxylic acids, particularly for 3-alkyl-3-methylenepropionic acids, which are challenging substrates for other chiral catalysts.

The 1,4-addition of organometallic reagents to enoates derived from pinanediol

The complex-induced, proximity effect-promoted 1,4-addition of RCu·BF3 and R2CuLi to enoates derived from (-)-pinanediol leads to adducts with the opposite sense of chirality (up to 98% d.e.).

Enantioselective carbolithiation of β-alkylated styrene

Stoichiometric or catalytic amounts of (-) sparteine serve as promoter for enantioselective carbolithiation of β-alkylated, non functionalized styrene.