574741-55-2

Basic information

• Product Name: 2-Propenoic acid, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-
• CAS NO: 574741-55-2
• Molecular Formula: C20H24O3Si
• Molecular Weight: 340.494
• Mol File: 574741-55-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(574741-55-2)
• EPA Substance Registry System: 2-Propenoic acid, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(574741-55-2)

Safety Data

• Hazardous Substances Data: 574741-55-2(Hazardous Substances Data)

Upstream product

• 646066-29-7 2-[(tert-butyl(diphenyl)silyloxy)methyl]acrylic acid ethyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1414883-12-7 N-benzyl 2-(tert-butyldiphenylsilanyloxymethyl)propenamide 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR PROTEIN LABELING, MODIFICATION, ANALYSIS, AND TARGETED DELIVERY

The invention relates to chemically reactive and/or biologically active compounds, reagents and compositions thereof. More particularly, the invention provides novel reagents that are useful in chemical synthesis, functionalization, delivery, probing and/or analytical measurements of small molecule drugs, proteins, antibodies and other biomolecules. The invention provides novel biologically active agents useful as diagnostics or therapeutics, and related composition and methods of uses thereof.

Parallel Kinetic Resolution of Intramolecular Furan Diels-Alder Cycloadducts via Asymmetric Hydroboration

We report parallel kinetic resolution of intramolecular Diels-Alder cycloadducts, where up to five stereocentres are defined using asymmetric hydroboration as the enantiodiscriminating reaction, and reveal evidence for dynamic kinetic resolution based on a reversible cycloaddition.

Synthesis of Denosomin-Vitamin D3 Hybrids and Evaluation of Their Anti-Alzheimer's Disease Activities

As an extension of previously conducted studies on developing an anti-Alzheimer's disease agent, denosomin (1-deoxy-24-norsominone, an artificial inducer of neurite elongation), derivatives were designed and synthesized based on the hypothesis that our denosomin would exhibit axonal extension activity via a 1,25D3-membrane-associated, rapid response steroid-binding protein (1,25D3-MARRS) pathway. The biological assay revealed that the hybridization of characteristic δ-lactone in denosomin and the triene moiety in VD3 was effective to enhance the nerve re-extension activity in amyloid β (Aβ)-damaged neurons.