574749-29-4

Basic information

• Product Name: 2H-1-Benzopyran-4-ol, 2-[3,4-bis(phenylmethoxy)phenyl]-3,4-dihydro-3,5,7-tris(phenylmethoxy)- , (2R,3S,4S)-
• CAS NO: 574749-29-4
• Molecular Formula: C50H44O7
• Molecular Weight: 756.895
• Mol File: 574749-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-4-ol, 2-[3,4-bis(phenylmethoxy)phenyl]-3,4-dihydro-3,5,7-tris(phenylmethoxy)- , (2R,3S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-4-ol, 2-[3,4-bis(phenylmethoxy)phenyl]-3,4-dihydro-3,5,7-tris(phenylmethoxy)- , (2R,3S,4S)-(574749-29-4)
• EPA Substance Registry System: 2H-1-Benzopyran-4-ol, 2-[3,4-bis(phenylmethoxy)phenyl]-3,4-dihydro-3,5,7-tris(phenylmethoxy)- , (2R,3S,4S)-(574749-29-4)

Safety Data

• Hazardous Substances Data: 574749-29-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 20728-73-8 5,7,3',4'-tetra-O-benzyl-(+)-catechin 
• 154-23-4 catechin 
• 478241-14-4 (+)-(4S)-acetoxy-3',4',3,5,7-penta-O-benzylcatechine 
• 85443-49-8 (2R,3S)-3,5,7-tris(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman 
• 100-44-7 benzyl chloride 

Downstream Products

• 574749-31-8 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 154-23-4 catechin 
• 480-18-2 taxifolin 
• 69256-15-1 (2R,3S,4R)-(+)-3,4,5,7,3',4'-hexahydroxyflavan 
• 478241-14-4 (+)-(4S)-acetoxy-3',4',3,5,7-penta-O-benzylcatechine 

Relevant articles and documents

NOVEL APPROACH FOR SYNTHESIS OF CATECHINS

A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+and/or?) epicatechin echm and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (?)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.

Stereoselective substitution of flavan skeletons: Synthesis of dryopteric acid

The C(4) acetoxylated catechin and epicatechin derivatives, 4 and 5, smoothly react with various nucleophiles under Lewis acidic conditions, giving C(4)-elaborated flavan-3-ols. Facile synthesis of dryopteric acid (3) was achieved.