57529-05-2

Basic information

• Product Name: 4-(1,3-DITHIAN-2-YL)PHENOL
• Synonyms: 4-(1,3-DITHIAN-2-YL)PHENOL;TIMTEC-BB SBB002383;2-(4-Hydroxyphenyl)-1,3-dithiane
• CAS NO: 57529-05-2
• Molecular Formula: C₁₀H₁₂OS₂
• Molecular Weight: 212.33
• Mol File: 57529-05-2.mol
• Article Data: 43

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(1,3-DITHIAN-2-YL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,3-DITHIAN-2-YL)PHENOL(57529-05-2)
• EPA Substance Registry System: 4-(1,3-DITHIAN-2-YL)PHENOL(57529-05-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 57529-05-2(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 55727-23-6 3‐(1,3-dithiane-2-yl)pentane-2,4-dione 
• 57529-04-1 2-chloro-1,3-dithiane 
• 461024-59-9 2-(1,3-dithian-2-ylidene)malonic acid 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 109-80-8 1.3-propanedithiol 
• 23639-82-9 p-hydroxybenzaldehyde ethylene glycol acetal 
• 6052-80-8 4-(2,6-dioxacyclohexyl)phenol 
• 156262-17-8 (4-(1,3-dithian-2-yl)phenoxy)(tert-butyl)dimethylsilane 
• 195054-29-6 2-[4'-acetoxyphenyl]-1,3-dithiane 
• 628300-14-1 2,4-dichloro-3-(1,3-propylenedithio-methylene)-penta-1,4-diene 

Downstream Products

• 74954-99-7 (2-Chloro-phenyl)-[2-(4-hydroxy-phenyl)-[1,3]dithian-2-yl]-methanone oxime 
• 123-08-0 4-hydroxy-benzaldehyde 
• 180839-16-1 di-tert-butyl N-<(4-<1,3-dithian-2-yl>phenyloxy)carbonyl>-L-glutamate 
• 872989-89-4 4-[2-(2-methoxy-5-thiophen-2-yl-benzyl)-[1,3]dithian-2-yl]-phenol 
• 219591-91-0 di-tert-butyl N-<(4-<amino>phenyl)carbamoyloxy>methyl>phenoxy)carbonyl>-L-glutamate 
• 180839-02-5 di-tert-butyl N-<(4-<amino>phenyl)carbamoyloxy>methyl>phenoxy)carbonyl>-L-glutamate 
• 180839-20-7 di-tert-butyl N-<(4-<<4-nitrophenoxycarbonyloxy>methyl>phenoxy)carbonyl>-L-glutamate 
• 180839-19-4 di-tert-butyl N-<(4-phenoxy)carbonyl>-L-glutamate 
• 180839-18-3 di-tert-butyl N-<(4-formylphenyloxy)carbonyl>-L-glutamate 

Relevant articles and documents

PhIO-Mediated oxidative dethioacetalization/dethioketalization under water-free conditions

Treatment of thioacetals and thioketals with iodosobenzene in anhydrous DCM conveniently afforded the corresponding carbonyl compounds in high yields under water-free conditions. The mechanistic studies indicate that this dethioacetalization/dethioketalization process does not need water and the oxygen of the carbonyl products comes from the hypervalent iodine reagent.

An expedient carbon–sulfur bond formation explored through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds

A facile carbon–sulfur bond formation was observed through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds. In a preliminary study, the synthesis and characterization of functionalized bio-polymer, cellulose sulph

A 2 - substituted - 1, 3 - dithiane derivative of the preparation method

The invention provides a preparation method of a 2-substituted-1,3-dithiane derivative. The preparation method comprises the following steps: adding 1,3-dithiane (CAS:505-23-7) and 1,2-dichloroethane (DCE) or dichloromethane (DCM) into a reaction bottle, adding N-chlorosuccinimide (NCS) under ice-bath condition, and stirring for 0.5-1 h to prepare a 2-chloro-1,3-dithiane solution; and adding an aldehyde or ketone compound and a lewis acid catalyst into the above solution, and reacting to prepare the 2-substituted-1,3-dithiane derivative. By using the 1,3-dithiane solid and different types of aldehyde and keto-carbonyl compounds as raw material and using one or more of ferric trichloride, boron trifluoride diethyl etherate, methanesulfonic acid, aluminum trichloride, ferrous chloride and nickel chloride as catalysts, preparation of the 2-substituted-1,3-dithiane derivative is realized. The catalysts used in the invention are cheap and easily available, dosage of the catalysts is low and pollution of the catalysts is little. The solid raw materials used in the invention can avoid use of fetid toxic 1,3-dimercaptopropane with strong volatility, and the purpose of protecting an experimenter's body and reducing environmental pollution is realized. In addition, the preparation method has advantages of mild reaction condition, high yield, simple operation and the like.